Bukhari Syed Nasir Abbas, Ahmed Naveed, Amjad Muhammad Wahab, Hussain Muhammad Ajaz, Elsherif Mervat A, Ejaz Hasan, Alotaibi Nasser H
Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka 72388, Saudi Arabia.
Department of Pharmaceutics, College of Pharmacy, Jouf University, Sakaka 72388, Saudi Arabia.
Polymers (Basel). 2023 Jan 4;15(2):267. doi: 10.3390/polym15020267.
Covalent organic frameworks (COFs), synthesized from organic monomers, are porous crystalline polymers. Monomers get attached through strong covalent bonds to form 2D and 3D structures. The adjustable pore size, high stability (chemical and thermal), and metal-free nature of COFs make their applications wider. This review article briefly elaborates the synthesis, types, and applications (catalysis, environmental Remediation, sensors) of COFs. Furthermore, the applications of COFs as biomaterials are comprehensively discussed. There are several reported COFs having good results in anti-cancer and anti-bacterial treatments. At the end, some newly reported COFs having anti-viral and wound healing properties are also discussed.
共价有机框架（COFs）由有机单体合成，是多孔结晶聚合物。单体通过强共价键连接形成二维和三维结构。COFs可调节的孔径、高稳定性（化学和热稳定性）以及无金属特性使其应用更加广泛。这篇综述文章简要阐述了COFs的合成、类型及其应用（催化、环境修复、传感器）。此外，还全面讨论了COFs作为生物材料的应用。有几篇报道称COFs在抗癌和抗菌治疗方面取得了良好效果。最后，还讨论了一些新报道的具有抗病毒和伤口愈合特性的COFs。
