Kuziez Lana, Eleiwa Taher K, Chauhan Muhammad Z, Sallam Ahmed B, Elhusseiny Abdelrahman M, Saeed Hajirah N
Saint Louis University School of Medicine, St. Louis, MO 63104, USA.
Department of Ophthalmology, Benha University, Benha 13518, Egypt.
Vaccines (Basel). 2023 Jan 12;11(1):166. doi: 10.3390/vaccines11010166.
Vaccines against coronavirus disease 2019 (COVID-19) have played an important global role in reducing morbidity and mortality from COVID-19 infection. While the benefits of vaccination greatly outweigh the risks, adverse events do occur. Non-ocular adverse effects of the vaccines have been well-documented, but descriptions of ophthalmic effects remain limited. This systematic review aims to provide an overview of reported cases of corneal adverse events after receiving vaccination against COVID-19 and to compile existing clinical data to bring attention to these phenomena. Our review discusses corneal graft rejection, including proposed mechanisms, herpetic keratitis, and other reported corneal complications. Ophthalmologists and primary care physicians should be aware of such possible associations.
2019冠状病毒病（COVID-19）疫苗在降低COVID-19感染的发病率和死亡率方面发挥了重要的全球作用。虽然接种疫苗的益处远大于风险，但不良事件确实会发生。疫苗的非眼部不良反应已有充分记录，但关于眼部影响的描述仍然有限。本系统综述旨在概述接种COVID-19疫苗后报告的角膜不良事件病例，并汇编现有临床数据以引起对这些现象的关注。我们的综述讨论了角膜移植排斥反应，包括提出的机制、疱疹性角膜炎以及其他报告的角膜并发症。眼科医生和初级保健医生应意识到此类可能的关联。
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