Department of Microbiology and Infection Control, University Hospital of North Norway, N-9038 Tromsø, Norway.
Metabolic and Renal Research Group, Department of Clinical Medicine, UiT The Arctic University of Norway, N-9037 Tromsø, Norway.
Viruses. 2022 Dec 29;15(1):89. doi: 10.3390/v15010089.
A recent paper in investigates the impact of the JC polyomavirus (JCPyV) microRNA on the replication of different JCPyV strains. Unfortunately, one of the cell lines used, the human fetal glial cell line SVGp12, is productively infected by the closely related BK polyomavirus (BKPyV), which may confound results. Scientists need to take this into account and the potential pitfalls.
最近的一篇论文研究了 JC 多瘤病毒 (JCPyV) 微 RNA 对不同 JCPyV 毒株复制的影响。不幸的是，所用的细胞系之一，人胎儿神经胶质细胞系 SVGp12，可被密切相关的 BK 多瘤病毒 (BKPyV) 有效感染，这可能会使结果复杂化。科学家们需要考虑到这一点和潜在的陷阱。
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