Alstadhaug Karl Bjørnar, Myhr Kjell-Morten, Rinaldo Christine Hanssen
Tidsskr Nor Laegeforen. 2017 Dec 12;137(23-24). doi: 10.4045/tidsskr.16.1092.
Progressive multifocal leukoencephalopathy is a rare, opportunistic infection of the central nervous system caused by the John Cunningham virus (JCV). There is no effective antiviral treatment available, and restoring immunocompetence is essential for survival. If this occurs too quickly, however, the inflammatory response may prove fatal. This is an up-to-date review of the disorder, intended for clinicians responsible for immunomodulatory therapy.
进行性多灶性白质脑病是一种由约翰·坎宁安病毒(JCV)引起的罕见的中枢神经系统机会性感染。目前尚无有效的抗病毒治疗方法,恢复免疫功能对于生存至关重要。然而,如果免疫功能恢复过快,炎症反应可能是致命的。这是一篇针对负责免疫调节治疗的临床医生的该疾病的最新综述。