Maria B, André-David F, Oury J F, Stampf F, Bresson E, Rosenberg P
Service de Gynécologie-Obstétrique, Centre Hospitalier, Villeneuve-Saint-Georges.
J Gynecol Obstet Biol Reprod (Paris). 1987;16(5):637-42.
Instrumental dilatation of the cervix prior to first trimester absorption may be difficult and source of complications. Pharmacological dilatation is proposed in a prospective random study using vaginal suppository containing 10 mg of 9-deoxo, 16-16 dimethyl, 9 methylene PGE2 (Meteneprost). Mean cervical dilatation, 3 hours after treatment, was significantly higher in the treated group (8.1 vs 6 mm) and additional dilatation was facilitated by cervical softening. Side effects occurred in most of the treated patients (uterine pain) but on a minor scale. This procedure may be considered as effective, safe and easy.
在孕早期流产前进行宫颈器械扩张可能困难且易引发并发症。在一项前瞻性随机研究中，有人提出使用含10毫克9-脱氧、16,16-二甲基、9-亚甲基前列腺素E2（米替前列醇）的阴道栓剂进行药物扩张。治疗3小时后，治疗组的平均宫颈扩张明显更高（8.1毫米对6毫米），宫颈软化有助于进一步扩张。大多数接受治疗的患者出现了副作用（子宫疼痛），但程度较轻。该方法可被认为是有效、安全且简便的。
