Yang Li, Yan Chenli, Wang Jingjing
Department of Hepatobiliary and Pancreatic Surgery, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Front Surg. 2023 Jan 6;9:1045003. doi: 10.3389/fsurg.2022.1045003. eCollection 2022.
Multi-disciplinary team (MDT) collaboration enables hepatocellular carcinoma (HCC) patients to achieve better survival through precise diagnosis and individualized treatment. This study aimed to further investigate the effect of MDT care program (MDT-CP) on quality of life (QoL), anxiety and depression in HCC patients after surgery.
Totally, 150 postoperative HCC patients were enrolled and randomized in a 1:1 ratio into the MDT-CP group ( = 76) to receive MDT care for 6 months and the normal care program (N-CP) group ( = 74) to receive routine care for 6 months.
Quality of Life Questionnaire-Core 30 (QLQ-C30) global health status score at 1 month (M1), M3 and M6, QLQ-C30 functions score at M3 and M6 elevated while QLQ-C30 symptom score at M1 and M3 decreased in MDT-CP group compared with N-CP group (all < 0.05). In addition, Hospital Anxiety and Depression Scale (HADS)-Anxiety score at M3 and M6, anxiety occurrence rate at M6, anxiety degree at M6, were all reduced in MDT-CP group compared with N-CP group (all < 0.05). HADS-Depression score at M6, and depression occurrence rate at M3, were both lessened in MDT-CP group compared to N-CP group (both < 0.05), while there was no distinction of depression degree at any time points between groups.
MDT-CP improves QoL, relieves anxiety and depression to a certain extent in HCC patients after surgery.
多学科团队(MDT)协作可使肝细胞癌(HCC)患者通过精确诊断和个体化治疗获得更好的生存效果。本研究旨在进一步探讨MDT护理方案(MDT-CP)对HCC患者术后生活质量(QoL)、焦虑和抑郁的影响。
共纳入150例HCC术后患者,按1:1比例随机分为MDT-CP组(n = 76),接受MDT护理6个月;正常护理方案(N-CP)组(n = 74),接受常规护理6个月。
与N-CP组相比,MDT-CP组在术后1个月(M1)、M3和M6时的生活质量问卷核心30项(QLQ-C30)总体健康状况评分,以及M3和M6时的QLQ-C30功能评分升高,而M1和M3时的QLQ-C30症状评分降低(均P < 0.05)。此外,与N-CP组相比,MDT-CP组在M3和M6时的医院焦虑抑郁量表(HADS)-焦虑评分、M6时的焦虑发生率、M6时的焦虑程度均降低(均P < 0.05)。与N-CP组相比,MDT-CP组在M6时的HADS-抑郁评分及M3时的抑郁发生率均降低(均P < 0.05),而两组在任何时间点的抑郁程度均无差异。
MDT-CP可改善HCC患者术后的生活质量,在一定程度上缓解焦虑和抑郁。