Krantz Morgan, Dalmacy Djhenne, Bishop Lauren, Hyer J Madison, Hand Brittany N
The Ohio State University.
University of Wisconsin Madison.
Res Autism Spectr Disord. 2023 Feb;100. doi: 10.1016/j.rasd.2022.102077. Epub 2022 Dec 1.
An emerging body of evidence suggests that autistic people are at greater risk for mortality than non-autistic people. Yet, relatively little is known about mortality rates among autistic people during older adulthood (i.e., age 65 or older).
We examined 5-year mortality among a national US sample of Medicare-enrolled autistic (n=3,308) and non-autistic (n=33,080) adults aged 65 or older.
Autistic older adults had 2.87 times greater rate of mortality (95% CI=2.61-3.07) than non-autistic older adults. Among decedents (39.6% of autistic and 15.1% of non-autistic older adults), the median age of death was 72 years (IQR=69-78) for autistic and 75 years (IQR=70-83) for non-autistic older adults. Among autistic older adults, those with intellectual disability had 1.57 times greater rate of mortality (95% CI=1.41-1.76) than those without, and males had 1.27 times greater rate of mortality (95% CI=1.12-1.43) than females.
Many trends regarding mortality observed in younger samples of autistic people were also observed in our study. However, we found only a three-year difference in median age at death between autistic and non-autistic decedents, which is a much smaller disparity than reported in some other studies. This potentially suggests that when autistic people live to the age of 65, they may live to a more similar age as non-autistic peers.
越来越多的证据表明,自闭症患者的死亡风险高于非自闭症患者。然而,对于老年期(即65岁及以上)自闭症患者的死亡率,我们所知相对较少。
我们在美国全国范围内对参加医疗保险的65岁及以上自闭症成年人(n = 3308)和非自闭症成年人(n = 33080)样本进行了5年死亡率研究。
自闭症老年成年人的死亡率比非自闭症老年成年人高2.87倍(95%置信区间=2.61 - 3.07)。在死亡者中(自闭症老年成年人占39.6%,非自闭症老年成年人占15.1%),自闭症老年成年人的死亡年龄中位数为72岁(四分位距=69 - 78),非自闭症老年成年人的死亡年龄中位数为75岁(四分位距=70 - 83)。在自闭症老年成年人中,有智力残疾的人的死亡率比没有智力残疾的人高1.57倍(95%置信区间=1.41 - 1.76),男性的死亡率比女性高1.27倍(95%置信区间=1.12 - 1.43)。
在我们的研究中也观察到了许多在自闭症患者较年轻样本中发现的与死亡率相关的趋势。然而,我们发现自闭症和非自闭症死亡者的死亡年龄中位数仅相差三年,这一差距比其他一些研究报告的要小得多。这可能表明,当自闭症患者活到65岁时,他们可能活到与非自闭症同龄人更相近的年龄。