Hosna Asma U, Miller Daniel, Makhoul Karim, Noff Nicole
Internal Medicine, Icahn School of Medicine at Mount Sinai, Queens Hospital Center, New York, USA.
Cureus. 2022 Dec 21;14(12):e32771. doi: 10.7759/cureus.32771. eCollection 2022 Dec.
Chronic thromboembolic pulmonary hypertension is a deadly condition that results from thrombus organization and formation of fibrous tissue in the large and/or middle-sized pulmonary artery; as a result, pulmonary vascular resistance increases resulting in pulmonary hypertension and right heart failure. Untreated chronic pulmonary embolism causes decompensated right heart failure. Early diagnosis and appropriate treatment are crucial for improving survival. Pulmonary endarterectomy (PEA) is the treatment of choice as it reduces pulmonary vascular resistance. For patients who are not a candidate for PEA, alternative treatment options improve quality of life.
慢性血栓栓塞性肺动脉高压是一种致命疾病,由大或中等大小肺动脉内血栓机化及纤维组织形成所致;结果,肺血管阻力增加,导致肺动脉高压和右心衰竭。未经治疗的慢性肺栓塞会导致失代偿性右心衰竭。早期诊断和恰当治疗对提高生存率至关重要。肺动脉内膜剥脱术(PEA)是首选治疗方法,因为它能降低肺血管阻力。对于不适合行PEA的患者,其他治疗选择可改善生活质量。