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一例慢性肺栓塞导致肺动脉高压和失代偿性右心衰竭的病例。

A Case of Chronic Pulmonary Embolism Resulting in Pulmonary Hypertension and Decompensated Right Heart Failure.

作者信息

Hosna Asma U, Miller Daniel, Makhoul Karim, Noff Nicole

机构信息

Internal Medicine, Icahn School of Medicine at Mount Sinai, Queens Hospital Center, New York, USA.

出版信息

Cureus. 2022 Dec 21;14(12):e32771. doi: 10.7759/cureus.32771. eCollection 2022 Dec.

DOI:10.7759/cureus.32771
PMID:36686131
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9853921/
Abstract

Chronic thromboembolic pulmonary hypertension is a deadly condition that results from thrombus organization and formation of fibrous tissue in the large and/or middle-sized pulmonary artery; as a result, pulmonary vascular resistance increases resulting in pulmonary hypertension and right heart failure. Untreated chronic pulmonary embolism causes decompensated right heart failure. Early diagnosis and appropriate treatment are crucial for improving survival. Pulmonary endarterectomy (PEA) is the treatment of choice as it reduces pulmonary vascular resistance. For patients who are not a candidate for PEA, alternative treatment options improve quality of life.

摘要

慢性血栓栓塞性肺动脉高压是一种致命疾病,由大或中等大小肺动脉内血栓机化及纤维组织形成所致;结果,肺血管阻力增加,导致肺动脉高压和右心衰竭。未经治疗的慢性肺栓塞会导致失代偿性右心衰竭。早期诊断和恰当治疗对提高生存率至关重要。肺动脉内膜剥脱术(PEA)是首选治疗方法,因为它能降低肺血管阻力。对于不适合行PEA的患者,其他治疗选择可改善生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1de/9853921/838a5cc9a156/cureus-0014-00000032771-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1de/9853921/3703fb3fae71/cureus-0014-00000032771-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1de/9853921/2da71b5d91ab/cureus-0014-00000032771-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1de/9853921/12b15259ccae/cureus-0014-00000032771-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1de/9853921/838a5cc9a156/cureus-0014-00000032771-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1de/9853921/3703fb3fae71/cureus-0014-00000032771-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1de/9853921/2da71b5d91ab/cureus-0014-00000032771-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1de/9853921/12b15259ccae/cureus-0014-00000032771-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1de/9853921/838a5cc9a156/cureus-0014-00000032771-i04.jpg

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J Clin Med. 2022 Jul 21;11(14):4224. doi: 10.3390/jcm11144224.
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Chronic thromboembolic pulmonary hypertension: the magic of pathophysiology.慢性血栓栓塞性肺动脉高压:病理生理学的奥秘
Ann Cardiothorac Surg. 2022 Mar;11(2):106-119. doi: 10.21037/acs-2021-pte-10.
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ERS statement on chronic thromboembolic pulmonary hypertension.ERS 关于慢性血栓栓塞性肺动脉高压的声明。
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Comparison of Balloon Pulmonary Angioplasty and Pulmonary Vasodilators for Inoperable Chronic Thromboembolic Pulmonary Hypertension: A Systematic Review and Meta-Analysis.无法手术的慢性血栓栓塞性肺动脉高压的球囊肺动脉成形术与肺血管扩张剂的比较:系统评价和荟萃分析。
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Incidence and risk factors of chronic thromboembolic pulmonary hypertension in patients with diagnosis of pulmonary embolism for the first time in real world.真实世界中首次诊断为肺栓塞患者慢性血栓栓塞性肺动脉高压的发病率及危险因素
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Chronic Thromboembolic Pulmonary Hypertension: An Update.慢性血栓栓塞性肺动脉高压:更新。
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