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肾上腺皮质髓质混合瘤，在正电子发射断层扫描/计算机断层扫描上表现出明显的F-氟脱氧葡萄糖活性，但无镓-多柔比星摄取。

Corticomedullary Mixed Tumor of the Adrenal Gland with Apparent F-Fluorodeoxyglucose Activity But No GA-DOTATATE Uptake on Positron Emission Tomography/Computed Tomography.

作者信息

Engur Ceren Ozge, Apaydın Tugce, Ones Tunc, Gozu Hulya Iliksu, Ozguven Salih

机构信息

Department of Nuclear Medicine, Marmara University, Pendik Training and Research Hospital, Istanbul, Turkey.

Department of Endocrinology and Metabolism, Marmara University, Pendik Training and Research Hospital, Istanbul, Turkey.

出版信息

Indian J Nucl Med. 2022 Jul-Sep;37(3):297-298. doi: 10.4103/ijnm.ijnm_194_21. Epub 2022 Nov 2.

DOI:10.4103/ijnm.ijnm_194_21
PMID:36686306
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9855236/
Abstract

Corticomedullary mixed tumor (CMT) is a single adrenal tumor mass composed histologically by an admixture of adrenal cortical and medullary cells. It is a rare condition, with approximately 20 cases reported to date. To our knowledge, the positron emission tomography (PET) imaging findings of this mostly benign tumor have not been reported in the literature. We present a case of CMT who was evaluated with both F-fluorodeoxyglucose (F-FDG) and Ga-DOTATATE. The hypermetabolic tumor seen on F-FDG PET/computed tomography scan showed no abnormal uptake by Ga-DOTATATE.

摘要

皮质髓质混合瘤（CMT）是一种单一的肾上腺肿瘤块，组织学上由肾上腺皮质和髓质细胞混合组成。它是一种罕见的病症，迄今为止报道的病例约有20例。据我们所知，这种大多为良性肿瘤的正电子发射断层扫描（PET）影像学表现尚未见文献报道。我们报告一例接受F-氟脱氧葡萄糖（F-FDG）和镓- DOTATATE评估的CMT病例。F-FDG PET/计算机断层扫描上所见的高代谢肿瘤在镓- DOTATATE检查中未显示异常摄取。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03ad/9855236/3415e618102d/IJNM-37-297-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03ad/9855236/3415e618102d/IJNM-37-297-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03ad/9855236/3415e618102d/IJNM-37-297-g001.jpg

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本文引用的文献

1
Current Concepts in Ga-DOTATATE Imaging of Neuroendocrine Neoplasms: Interpretation, Biodistribution, Dosimetry, and Molecular Strategies.神经内分泌肿瘤镓- DOTATATE成像的当前概念：解读、生物分布、剂量测定及分子策略
J Nucl Med. 2017 Nov;58(11):1718-1726. doi: 10.2967/jnumed.116.186361. Epub 2017 Aug 17.
2
Spectrum of 68Ga-DOTA TATE Uptake in Patients With Neuroendocrine Tumors.68Ga-DOTA TATE 摄取在神经内分泌肿瘤患者中的谱。
Clin Nucl Med. 2016 Jun;41(6):e281-7. doi: 10.1097/RLU.0000000000001100.
3
Imaging Features of Various Adrenal Neoplastic Lesions on Radiologic and Nuclear Medicine Imaging.
各种肾上腺肿瘤性病变在放射学和核医学成像上的影像特征
AJR Am J Roentgenol. 2015 Sep;205(3):554-63. doi: 10.2214/AJR.15.14467.
4
Somatostatin receptor imaging with 68Ga DOTATATE PET/CT: clinical utility, normal patterns, pearls, and pitfalls in interpretation.68Ga-DOTATATE PET/CT 进行生长抑素受体显像：临床应用、正常表现、解读要点及陷阱。
Radiographics. 2015 Mar-Apr;35(2):500-16. doi: 10.1148/rg.352140164.
5
Mixed corticomedullary adrenal carcinoma.混合型皮质-髓质肾上腺皮质癌。
Surg Today. 2013 Nov;43(11):1232-9. doi: 10.1007/s00595-012-0458-4. Epub 2013 Feb 23.
6
Mixed corticomedullary carcinoma of the adrenal gland: a case report.肾上腺混合性皮质-髓质癌：病例报告。
Endocr Pract. 2012 May-Jun;18(3):e37-42. doi: 10.4158/EP11222.CR.
7
The Weiss score and beyond--histopathology for adrenocortical carcinoma.魏斯评分与超越：肾上腺皮质癌的组织病理学。
Horm Cancer. 2011 Dec;2(6):333-40. doi: 10.1007/s12672-011-0088-0.
8
Corticomedullary mixed tumor of the adrenal gland.肾上腺皮质-髓质混合瘤。
Ann Endocrinol (Paris). 2009 Dec;70(6):473-6. doi: 10.1016/j.ando.2009.09.003. Epub 2009 Oct 29.
9
Corticomedullary mixed tumor of the adrenal gland.肾上腺皮质髓质混合瘤
Ann Diagn Pathol. 2001 Oct;5(5):304-8. doi: 10.1053/adpa.2001.28297.
10
Imaging of adrenal tumors using FDG PET: comparison of benign and malignant lesions.使用氟代脱氧葡萄糖正电子发射断层显像（FDG PET）对肾上腺肿瘤进行成像：良性与恶性病变的比较
AJR Am J Roentgenol. 1999 Jul;173(1):25-9. doi: 10.2214/ajr.173.1.10397094.