Ayhan Nazli, Rodríguez-Teijeiro José Domingo, López-Roig Marc, Vinyoles Dolors, Ferreres Josep Anton, Monastiri Abir, Charrel Remi, Serra-Cobo Jordi
Unité des Virus Emergents (UVE: Aix-Marseille Université, IRD 190, INSERM 1207), Marseille, France.
Departament de Biologia Evolutiva, Ecologia i Ciències Ambientals, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain.
Front Microbiol. 2023 Jan 4;13:1091908. doi: 10.3389/fmicb.2022.1091908. eCollection 2022.
Birds are involved natural cycle of a number of vector-borne viruses in both rural and urban areas. Toscana (TOSV) and Sicilian (SFSV) phleboviruses are sandfly-borne viruses in the genus that can cause diseases in human. However, there is limited information on the role of the birds in sandfly-borne phleboviruses natural cycle and reservoirs ofthese viruses remain unknown.
In this study, we analyzed Common Quail () sera from Spain to identify the seroprevalence of these two phleboviruses. We tested respectively, 106 and 110 quail serum against TOSV and SFSV from 2018, 2019, and 2021 from two locations in northern Spain with using virus neutralization test.
We identified high neutralizing antibody rates for SFSV (45.45%) and TOSV (42.45%) with yearly fluctuation.
This is the first identification of SFSV and TOSV neutralizing antibodies in wild birds. High seroprevalence rates of TOSV and SFSV in quail birds raises the question whether birds have a role as amplifying hosts in the natural cycle of phleboviruses.
鸟类参与了农村和城市地区多种媒介传播病毒的自然循环。托斯卡纳病毒（TOSV）和西西里病毒（SFSV）属于白蛉传播病毒，可导致人类患病。然而，关于鸟类在白蛉传播病毒自然循环中的作用信息有限，且这些病毒的宿主仍不清楚。
在本研究中，我们分析了来自西班牙的普通鹌鹑血清，以确定这两种病毒的血清阳性率。我们分别使用病毒中和试验，检测了2018年、2019年和2021年从西班牙北部两个地点采集的106份和110份鹌鹑血清中的TOSV和SFSV。
我们发现SFSV（45.45%）和TOSV（42.45%）的中和抗体率较高，且存在年度波动。
这是首次在野生鸟类中鉴定出SFSV和TOSV中和抗体。鹌鹑中TOSV和SFSV的高血清阳性率引发了一个问题，即鸟类是否在白蛉病毒的自然循环中充当扩增宿主。
