Röck Tobias, Bösmüller Hans-Christian, Bartz-Schmidt Karl Ulrich, Röck Daniel
Centre for Ophthalmology, University of Tübingen, Tübingen, Germany,
Institute of Pathology and Neuropathology, University of Tübingen, Tübingen, Germany.
Int Med Case Rep J. 2018 Jul 27;11:161-165. doi: 10.2147/IMCRJ.S164099. eCollection 2018.
Nevi of the conjunctiva are usually benign pigmented tumorous lesions located in the bulbar conjunctiva. In most conjunctival nevus cases, the patient wants the lesion to be removed for cosmetic reasons, but excisional biopsies are best for lesions suspicious for malignancy. This case report illustrates the intraoperative surgical management, histological findings, and the course of healing in a conjunctival nevus patient.
A 26-year-old man was referred to our eye hospital with a large bulbar conjunctival nevus of the right eye. Upon examination, there was a large pigmented lesion with numerous small cysts present on the superior bulbar conjunctiva. The conjunctival tumor was resected, and an amniotic membrane transplantation was performed for the bulbar conjunctival reconstruction. The histopathological diagnosis suggested a conjunctival nevus. After the resection, a reduction in the inflammation and healing of the conjunctival lesion could be seen. The epithelialization of the bulbar conjunctiva over the amniotic membrane was complete 4 weeks after the resection. At the 6-month follow-up, there was no sign of recurrence or any postoperative complications.
A surgical excision combined with reconstruction via amniotic membrane transplantation is effective and economical for the treatment of large conjunctival lesions.
结膜痣通常是位于球结膜的良性色素性肿瘤性病变。在大多数结膜痣病例中，患者因美容原因希望切除病变，但对于可疑恶性的病变，切除活检是最佳选择。本病例报告阐述了一名结膜痣患者的术中手术管理、组织学检查结果及愈合过程。
一名26岁男性因右眼巨大球结膜痣转诊至我院眼科。检查发现，球结膜上方有一个巨大色素性病变，伴有许多小囊肿。切除结膜肿瘤，并进行羊膜移植以重建球结膜。组织病理学诊断为结膜痣。切除术后，可见结膜病变的炎症减轻且愈合。切除术后4周，羊膜上方的球结膜上皮化完成。在6个月的随访中，没有复发迹象或任何术后并发症。
手术切除联合羊膜移植重建对于治疗大型结膜病变有效且经济。
