American College of Physicians, Philadelphia, Pennsylvania (A.Q., I.E-I.).
Stanford Health Policy, Stanford University, Stanford, California (D.K.O.).
Ann Intern Med. 2023 Feb;176(2):239-252. doi: 10.7326/M22-2056. Epub 2023 Jan 24.
The purpose of this guideline from the American College of Physicians (ACP) is to present updated clinical recommendations on nonpharmacologic and pharmacologic interventions as initial and second-line treatments during the acute phase of a major depressive disorder (MDD) episode, based on the best available evidence on the comparative benefits and harms, consideration of patient values and preferences, and cost.
The ACP Clinical Guidelines Committee based these recommendations on an updated systematic review of the evidence.
The audience for this guideline includes clinicians caring for adult patients in the acute phase of MDD in ambulatory care. The patient population includes adults in the acute phase of MDD.
RECOMMENDATION 1A:
RECOMMENDATION 1B:
RECOMMENDATION 2:
RECOMMENDATION 3: • •
美国医师学院（ACP）的本指南旨在根据现有最佳证据，就非药物和药物干预措施在重度抑郁症（MDD）发作的急性期作为一线和二线治疗方法，提出更新的临床建议。这些建议考虑了比较效益和危害、患者价值观和偏好以及成本。
ACP 临床指南委员会根据对证据的更新系统评价制定了这些建议。
本指南的受众包括在门诊环境中照顾 MDD 急性期成年患者的临床医生。患者人群包括 MDD 急性期的成年人。
推荐 1A：
推荐 1B：
推荐 2：
推荐 3：• •
