Alverson D C, Aldrich M, Angelus P, Backstrom C, Werner S
Department of Pediatrics, University of New Mexico School of Medicine, Albuquerque 87131.
J Ultrasound Med. 1987 Sep;6(9):519-24. doi: 10.7863/jum.1987.6.9.519.
We studied left ventricular (LV) cardiac output as estimated by ascending aorta blood flow (QAo) longitudinally in 31 healthy infants from birth through the first year of life using noninvasive pulsed Doppler ultrasound technique. The temporal mean ascending aortic blood flow velocity (VAo) was measured with a 5-MHz pulsed Doppler velocimeter and on line integration system. Ascending aortic cross-sectional area (AAo) was determined using M-mode echography. Ascending aortic blood flow was calculated as QAo = VAo X AAo and was corrected to body weight (BW) in kilograms or body surface area (BSA) in meters squared. Mean ascending aortic flow velocity (VAo) remained relatively constant over the first year, averaging 20.5 +/- 3.4 cm/sec (+/- SD). Changes in AAo over time correlated strongly with changes in BW or BSA (r = 0.99). Therefore, changes in QAo correlated strongly with changes in AAo, BW, and BSA (r = 0.99). LV cardiac output corrected for body weight or BSA remained relatively constant throughout the first year, mean values ranging from 180-226 ml/min/kg or 3.06-3.76 L/min/m2 and averaging 204 +/- 45 ml/min/kg or 3.48 +/- 0.74 L/min/m2. A similar strong correlation was seen between serial changes in LV stroke volume and changes in BW or BSA (r = 0.99).
我们使用无创脉冲多普勒超声技术，对31名健康婴儿从出生到1岁进行纵向研究，以升主动脉血流量（QAo）估算左心室（LV）心输出量。使用5兆赫脉冲多普勒测速仪和在线积分系统测量升主动脉血流速度的时间平均值（VAo）。使用M型超声心动图测定升主动脉横截面积（AAo）。升主动脉血流量计算为QAo = VAo×AAo，并校正为以千克为单位的体重（BW）或以平方米为单位的体表面积（BSA）。在第一年中，升主动脉平均流速（VAo）保持相对恒定，平均为20.5±3.4厘米/秒（±标准差）。AAo随时间的变化与BW或BSA的变化密切相关（r = 0.99）。因此，QAo的变化与AAo、BW和BSA的变化密切相关（r = 0.99）。校正体重或BSA后的左心室心输出量在整个第一年中保持相对恒定，平均值在180 - 226毫升/分钟/千克或3.06 - 3.76升/分钟/平方米之间，平均为204±45毫升/分钟/千克或3.48±0.74升/分钟/平方米。左心室每搏输出量的系列变化与BW或BSA的变化之间也存在类似的强相关性（r = 0.99）。
