Am J Epidemiol. 2023 May 5;192(5):736-747. doi: 10.1093/aje/kwad016.
In the present study, we examined the associations between physical characteristics of neighborhoods and sleep health outcomes and assessed the mediating role of physical activity in these associations. A longitudinal study (the Pittsburgh Hill/Homewood Research on Eating, Shopping, and Health (PHRESH) Zzz Study; n = 1,051) was conducted in 2 low-income, predominately African-American neighborhoods in Pittsburgh, Pennsylvania, with repeated measures of neighborhood characteristics and sleep health outcomes from 2013 to 2018. Built environment measures of walkability, urban design, and neighborhood disorder were captured from systematic field observations. Sleep health outcomes included insufficient sleep, sleep duration, wakefulness after sleep onset, and sleep efficiency measured from 7-day actigraphy data. G-computations based on structural nested mean models were used to examine the total effects of each built environment feature, and causal mediation analyses were used to evaluate direct and indirect effects operating through physical activity. Urban design features were associated with decreased wakefulness after sleep onset (risk difference (RD) = -1.26, 95% confidence interval (CI): -4.31, -0.33). Neighborhood disorder (RD = -0.46, 95% CI: -0.86, -0.07) and crime rate (RD = -0.54, 95% CI: -0.93, -0.08) were negatively associated with sleep efficiency. Neighborhood walkability was not associated with sleep outcomes. We did not find a strong and consistent mediating role of physical activity. Interventions to improve sleep should target modifiable factors, including urban design and neighborhood disorder.
在本研究中,我们研究了邻里的物理特征与睡眠健康结果之间的关联,并评估了身体活动在这些关联中的中介作用。这是一项纵向研究(匹兹堡希尔/霍姆伍德饮食、购物和健康研究(PHRESH Zzz 研究);n=1051),在宾夕法尼亚州匹兹堡的两个低收入、以非裔美国人为主的社区进行,从 2013 年到 2018 年,对邻里特征和睡眠健康结果进行了重复测量。通过系统的实地观察,获取了可步行性、城市设计和邻里混乱等建筑环境措施的测量值。睡眠健康结果包括通过 7 天活动记录仪数据测量的睡眠不足、睡眠时间、入睡后醒来和睡眠效率。基于结构嵌套均值模型的 G 计算用于检验每个建筑环境特征的总效应,因果中介分析用于评估通过身体活动运作的直接和间接效应。城市设计特征与入睡后醒来的时间减少有关(风险差异(RD)=-1.26,95%置信区间(CI):-4.31,-0.33)。邻里混乱(RD=-0.46,95%CI:-0.86,-0.07)和犯罪率(RD=-0.54,95%CI:-0.93,-0.08)与睡眠效率呈负相关。邻里可步行性与睡眠结果无关。我们没有发现身体活动的强大和一致的中介作用。改善睡眠的干预措施应针对可改变的因素,包括城市设计和邻里混乱。