大麻与睡眠障碍：尚未成熟？一项定性范围综述。

Cannabis and sleep disorders: not ready for prime time? A qualitative scoping review.

机构信息

Department of Medicine, University Centre of the Americas, São Paulo, São Paulo, Brazil.

KITE-Toronto Rehabilitation Institute, University Health Network and Division of Physical Medicine and Rehabilitation, University of Toronto, Toronto, Ontario, Canada.

出版信息

J Clin Sleep Med. 2023 May 1;19(5):975-990. doi: 10.5664/jcsm.10428.

DOI:10.5664/jcsm.10428

PMID:36692176

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10152356/

Abstract

STUDY OBJECTIVES

To perform a qualitative scoping literature review for studies involving the effects of cannabis on sleep and sleep disorders.

METHODS

Two electronic databases, MEDLINE and EMBASE, searched for comprehensive published abstracted studies that involved human participants. Inclusion criteria were article of any type, published in English, a target population of cannabis users, and reported data on cannabis effect on sleep and sleep disorders. The Joanna Briggs Institute's (JBI) approach was elected as the methodology framework guidance in the scoping review process.

RESULTS

A total of 40 unique publications were found. The majority (82.5%) were from the Americas with 60% published in the last decade. Of the 40 studies, only 25% were randomized control trials, and the sleep outcome measurements were similar and comparable in only 20%. Cannabis users studied were reported either 73% frequent users or 27% sporadic users. The utilization of cannabis showed improved sleep (21%), worse sleep (48%), mixed results (14%), or no impact at all (17%) in the studies published in the last 5 decades.

CONCLUSIONS

Our findings summarize the lack of robust evidence to support the use of cannabis for sleep disorders. The varied cannabis user-related characteristics may account for the inconsistent results identified. Further studies assessing cannabis and sleep are needed to discern what works in what context, how it works, and for whom.

CITATION

Amaral C, Carvalho C, Scaranelo A, Chapman K, Chatkin J, Ferreira I. Cannabis and sleep disorders: not ready for prime time? A qualitative scoping review. . 2023;19(5):975-990.

摘要

研究目的

对涉及大麻对睡眠和睡眠障碍影响的研究进行定性范围综述。

方法

在 MEDLINE 和 EMBASE 两个电子数据库中搜索了全面发表的摘要研究，这些研究涉及人类参与者。纳入标准是任何类型的文章，发表在英语中，目标人群是大麻使用者，并报告了大麻对睡眠和睡眠障碍影响的数据。乔安娜·布里格斯研究所（JBI）的方法被选为范围综述过程中的方法框架指南。

结果

共发现 40 篇独特的出版物。其中大多数（82.5%）来自美洲，其中 60%发表于过去十年。在这 40 项研究中，只有 25%是随机对照试验，只有 20%的睡眠结果测量相似且可比较。研究中报告的大麻使用者要么是 73%的高频使用者，要么是 27%的偶发性使用者。在过去 50 年发表的研究中，大麻的使用显示出改善睡眠（21%）、睡眠质量下降（48%）、结果混合（14%）或根本没有影响（17%）。

结论

我们的研究结果总结了缺乏有力证据支持大麻治疗睡眠障碍的使用。与大麻使用者相关的特征的多样性可能是造成结果不一致的原因。需要进一步研究大麻和睡眠，以确定在什么情况下、如何以及对谁有效。

引文

Amaral C, Carvalho C, Scaranelo A, Chapman K, Chatkin J, Ferreira I. Cannabis and sleep disorders: not ready for prime time? A qualitative scoping review.. 2023;19(5):975-990.