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引言:肾功能代偿性适应及肾代偿性肥大的历史与问题。

Introduction: history and problems of compensatory adaptation of renal functions and of compensatory hypertrophy of the kidney.

作者信息

Peters G

出版信息

Yale J Biol Med. 1978 May-Jun;51(3):235-45.

Abstract

The history of observations and experimental work on compensatory changes following the loss of renal mass, and the historical reasons for the distinction between the concepts of compensatory adaptation (of renal functions) and of compensatory hypertrophy (of nephrons) are outlined. While the effector mechanisms of both types of compensatory changes are being elucidated at a rapid pace, many questions concerning the primary changes initiating these events, the control mechanisms implied and the interrelationship between functional adaptation and hypertrophy remain unanswered.

摘要

本文概述了肾实质丧失后代偿性变化的观察和实验工作历史,以及区分(肾功能的)代偿性适应和(肾单位的)代偿性肥大这两个概念的历史原因。虽然这两种代偿性变化的效应机制正在迅速阐明,但许多关于引发这些事件的初始变化、隐含的控制机制以及功能适应与肥大之间的相互关系的问题仍未得到解答。

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Compensatory renal hypertrophy in fetal lambs.胎儿羔羊的代偿性肾肥大。
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Functional adaptation during renal compensatory growth.
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本文引用的文献

1
The secretion of urine.尿液的分泌。
J Physiol. 1910 Nov 9;41(3-4):145-67. doi: 10.1113/jphysiol.1910.sp001397.
7
Compensatory renal hypertrophy.代偿性肾肥大
J Urol. 1962 Jul;88:11-8. doi: 10.1016/S0022-5347(17)64727-X.

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