Iwase H, Uno M, Tsujii T, Ikeshita H, Hogaki M, Arai K
Department of Obstetrics and Gynecology, School of Medicine, Teikyo University.
Jpn J Antibiot. 1987 May;40(5):1037-40.
Seventeen patients with gynecological infections (5 cases each of Bartholin's abscess and adnexitis, 4 cases of endometritis and 1 case each of bartholinitis, pyosalpinx and vulvar abscess) were treated with cefuzonam (CZON, L-105) administered by intravenous drip infusion, 1-2 g twice daily, for 4 to 12 days (6 g to 23 g in total). The clinical effectiveness reached 94.1%, including 1 excellent case, 15 cases good, and a poor case. Bacteria were detected in 9 cases, and with CZON treatment, bacterial eradications were obtained in 6 case, but, in 3 cases, bacterial replacements were observed. No abnormal laboratory findings were noted. From the above results, CZON seemed to be a highly effective and useful agent for gynecological infections.
17例妇科感染患者（巴氏腺脓肿和附件炎各5例，子宫内膜炎4例，巴氏腺炎、输卵管积脓和外阴脓肿各1例）接受头孢唑南（CZON，L - 105）静脉滴注治疗，每日2次，每次1 - 2 g，疗程4至12天（总量6 g至23 g）。临床有效率达94.1%，其中显效1例，有效15例，无效1例。9例检出细菌，经CZON治疗后，6例细菌清除，但3例出现细菌替换。未发现实验室检查异常。根据上述结果，头孢唑南似乎是治疗妇科感染的一种高效且有用的药物。
