Souma A, Yamashita K, Ishikawa M, Yorozu Y, Asakawa T, Shimizu T, Haga H, Saitoh S, Saitoh T, Hasegawa T
Department of Obstetrics and Gynecology, Asahikawa Medical College.
Jpn J Antibiot. 1987 Sep;40(9):1617-23.
Cefuzonam (CZON, L-105), a cephem type antibiotic, was clinically studied in the field of obstetrics and gynecology. The results are summarized as follows: CZON 1-2 g was administered by injection twice daily to 11 cases of infections (4 of endometritis, 2 of pyometra, 3 of adnexitis and peritonitis, 1 of abdominal abscess, and 1 of puerperal fever). Clinical efficacy was excellent in 2 cases and good in 9 cases, with a very high overall efficacy rate of 100%. Slight elevations of GOT and GPT in 1 case were noted in clinical laboratory tests. No side effects attributable to the drug were noted. CZON is considered to be a useful drug for obstetric and gynecological infections.
头孢唑南（CZON，L - 105），一种头孢烯类抗生素，在妇产科领域进行了临床研究。结果总结如下：对11例感染患者（子宫内膜炎4例、积脓2例、附件炎和腹膜炎3例、腹腔脓肿1例、产褥热1例）每日两次注射1 - 2克头孢唑南。临床疗效为优2例，良9例，总有效率高达100%。临床实验室检查发现1例谷草转氨酶（GOT）和谷丙转氨酶（GPT）略有升高。未观察到该药物引起的副作用。头孢唑南被认为是治疗妇产科感染的有效药物。
