Chimura T, Watanabe T, Inoue K, Yoshimura Y
Department of Obstetrics and Gynecology, School of Medicine, Yamagata University.
Jpn J Antibiot. 1987 May;40(5):995-1000.
Clinical studies of cefuzonam (CZON, L-105) were performed in patients of obstetrics and gynecology, and the results obtained are summarized below. 1. CZON was intravenously administered at a daily dose of 1-2 g to 11 cases including 3 cases with intrauterine infection (pyometra), 2 cases of intrapelvic infection (1 case of pelvic dead space infection and 1 case of pelvic peritonitis), 1 case of adnexitis, and others (2 cases of vaginal cuff infection, and 1 case each of vaginal abscess, Baltholin's abscess, and vulvar abscess). Clinical efficacy was excellent in 1 case and good in 10 cases. 2. CZON showed a good antibacterial effect in single and mixed infections. 3. Neither side effects nor abnormal values in clinical laboratory findings attributable to the drug were observed.
对头孢唑南(CZON,L - 105)进行了妇产科患者的临床研究,所得结果总结如下。1. 对11例患者静脉注射头孢唑南,日剂量为1 - 2g,其中包括3例子宫内感染(积脓)、2例盆腔内感染(1例盆腔死腔感染和1例盆腔腹膜炎)、1例附件炎以及其他病例(2例阴道残端感染,阴道脓肿、巴氏腺脓肿和外阴脓肿各1例)。临床疗效为1例优秀,10例良好。2. 头孢唑南在单一感染和混合感染中均显示出良好的抗菌效果。3. 未观察到因该药物引起的副作用或临床实验室检查结果异常。