Mardenli Mahmoud, Ghabally Mike, Horo Barkhodan, Alkhatib Qais, Raee Malek
Department of Internal Medicine, University of Aleppo, Aleppo, Syria.
Faculty of Medicine, Department of Internal Medicine, Division of Cardiology, Aleppo, Syria.
Oxf Med Case Reports. 2023 Jan 18;2023(1):omac145. doi: 10.1093/omcr/omac145. eCollection 2023 Jan.
Alveolar hemorrhage following thrombolytic agents administration is an extremely rare entity that has only been reported in twenty two patients in the medical literature. We herein report a case of a 60-year old male with an acute ST-elevation myocardial infarction who was treated with Streptokinase. Twelve hours after streptokinase adminstration, the patient developed severe hemoptysis and dyspnea and radiological studies were highly suggestive for acute alveolar hemorrhage. His past medical history is significant for severe chest trauma ten months prior to presentation. . Conservative therapy in addition to anti-coagulants withdrawal has led to gradual improvement in the next six days. We also discussed the aspects of our patient in comparison with published cases.
溶栓药物给药后发生的肺泡出血是一种极其罕见的情况,医学文献中仅报道过22例患者。我们在此报告一例60岁男性急性ST段抬高型心肌梗死患者,接受了链激酶治疗。链激酶给药12小时后,患者出现严重咯血和呼吸困难,影像学检查高度提示急性肺泡出血。他的既往病史显示在就诊前10个月曾遭受严重胸部创伤。除停用抗凝剂外,保守治疗使患者在接下来的6天里逐渐好转。我们还将我们的患者与已发表病例进行了对比讨论。