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溶栓治疗后肺泡出血

Pulmonary alveolar hemorrhage following thrombolytic therapy.

作者信息

Narayanan Santhosh, Thulaseedharan N K, Subramaniam Gomathy, Panarkandy Geetha, Arathi Narayanan

机构信息

Department of Medicine.

Department of Radiodiagnosis, Government Medical College, Kozhikode, Kerala, India.

出版信息

Int Med Case Rep J. 2017 Apr 4;10:123-125. doi: 10.2147/IMCRJ.S129087. eCollection 2017.

DOI:10.2147/IMCRJ.S129087
PMID:28435331
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5388342/
Abstract

We report a case of a 58-year-old male without any comorbidities who was thrombolysed with streptokinase for acute anterior wall myocardial infarction and developed massive hemoptysis with dyspnea and imaging features showing bilateral alveolar infiltrates. He was diagnosed with pulmonary alveolar hemorrhage and treated conservatively. His condition improved, and follow-up imaging showed resolution. Alveolar hemorrhage is a rare and life-threatening complication of thrombolytic therapy.

摘要

我们报告一例58岁男性，无任何合并症，因急性前壁心肌梗死接受链激酶溶栓治疗，随后出现大量咯血伴呼吸困难，影像学表现为双侧肺泡浸润。他被诊断为肺泡出血并接受保守治疗。其病情好转，后续影像学检查显示病变消退。肺泡出血是溶栓治疗罕见且危及生命的并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ef3/5388342/bde894cfdc12/imcrj-10-123Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ef3/5388342/df9f6266d2f9/imcrj-10-123Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ef3/5388342/e670f709d647/imcrj-10-123Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ef3/5388342/bde894cfdc12/imcrj-10-123Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ef3/5388342/df9f6266d2f9/imcrj-10-123Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ef3/5388342/e670f709d647/imcrj-10-123Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ef3/5388342/bde894cfdc12/imcrj-10-123Fig3.jpg

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本文引用的文献

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Diffuse alveolar hemorrhage as a complication of dual antiplatelet therapy for acute coronary syndrome.弥漫性肺泡出血作为急性冠状动脉综合征双联抗血小板治疗的并发症
Cardiovasc Revasc Med. 2011 Nov-Dec;12(6):407-11. doi: 10.1016/j.carrev.2011.03.003. Epub 2011 Apr 21.
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Alveolar haemorrhage in the immunocompetent host: a scale for early diagnosis of an immune cause.免疫功能正常宿主的肺泡出血：用于早期诊断免疫病因的量表。
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Diffuse alveolar haemorrhage: factors associated with in-hospital and long-term mortality.
急性心肌梗死溶栓治疗后肺泡出血：两例报告及文献综述
Open Access Emerg Med. 2021 Aug 27;13:399-405. doi: 10.2147/OAEM.S324366. eCollection 2021.
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Treatment of ST-Segment Elevation Myocardial Infarction During COVID-19 Pandemic.2019冠状病毒病大流行期间ST段抬高型心肌梗死的治疗
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Pulmonary haemorrhage following thrombolysis with streptokinase in myocardial infarction.心肌梗死患者使用链激酶溶栓后发生肺出血。
BMJ Case Rep. 2020 Jan 23;13(1):e232308. doi: 10.1136/bcr-2019-232308.
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Diffuse alveolar hemorrhage following intravenous thrombolytic treatment in acute ischemic stroke: a case series.静脉溶栓治疗急性缺血性脑卒中后弥漫性肺泡出血：病例系列。
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弥漫性肺泡出血：与院内和长期死亡率相关的因素。
Eur Respir J. 2010 Jun;35(6):1303-11. doi: 10.1183/09031936.00075309. Epub 2009 Oct 19.
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Severe respiratory failure due to diffuse alveolar hemorrhage: clinical characteristics and outcome of intensive care.弥漫性肺泡出血致严重呼吸衰竭：重症监护的临床特征和结局。
J Crit Care. 2010 Jun;25(2):230-5. doi: 10.1016/j.jcrc.2009.04.009. Epub 2009 Jul 9.
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Aetiologies and outcomes of diffuse alveolar haemorrhage presenting as acute respiratory failure of uncertain cause.表现为病因不明的急性呼吸衰竭的弥漫性肺泡出血的病因及转归
Respirology. 2009 Mar;14(2):290-4. doi: 10.1111/j.1440-1843.2008.01444.x. Epub 2008 Dec 11.
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Diffuse alveolar hemorrhage: diagnosing it and finding the cause.弥漫性肺泡出血：诊断及病因查找
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Diffuse pulmonary hemorrhage after streptokinase administration for acute myocardial infarction.急性心肌梗死患者应用链激酶后发生弥漫性肺出血。
Pharmacotherapy. 1997 Mar-Apr;17(2):390-4.
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Diffuse pulmonary hemorrhage complicating thrombolytic therapy for acute myocardial infarction.急性心肌梗死溶栓治疗并发弥漫性肺出血。
Clin Cardiol. 1997 Mar;20(3):298-300. doi: 10.1002/clc.4960200321.
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Pulmonary hemorrhage following intravenous streptokinase for acute myocardial infarction.静脉注射链激酶治疗急性心肌梗死后发生肺出血。
Int J Cardiol. 1990 Dec;29(3):387-90. doi: 10.1016/0167-5273(90)90132-o.
10
Spontaneous pulmonary hemorrhage following coronary thrombolysis.冠状动脉溶栓后自发性肺出血。
Chest. 1992 Apr;101(4):1150-2. doi: 10.1378/chest.101.4.1150.