Namazi Parviz, Fatemi Mohammad Javad, Pahlevanpour Parisa, Abbastabar Hedayat, Naderi Gharahgheshlagh Soheila
Burn Research Center, Iran University of Medical Sciences, Tehran, Iran.
Department of Plastic and Recons-tructive Surgery, Hazrat Fatemeh Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
World J Plast Surg. 2022;11(3):55-62. doi: 10.52547/wjps.11.3.55.
Burns are among the major health challenges of all societies and more than any other trauma incur physical, mental, social, and economic burdens on the patient and society. This study was conducted to assess whether Recove burn ointment is capable of alleviating the pain, preventing the formation of new blisters and controlling the microbial contamination of the wound.
We, therefore, compared its efficacy to % cream. This randomized clinical trial was conducted on individuals who had two burn injuries in their body at the same time in the Motahari Burn Hospital, Tehran Province, from June to October 2016. Sampling was carried out with a non-random method using available samples. The intervention in experimental and control groups was Recove and , respectively. The effect of interventions on pain relief, the formation of new blisters and prevention of infection at the burn wound were evaluated. In our double-blind study, blindness was applied to the patients and the person evaluating the outcomes.
Both Recove and nitrofurazone interventions significantly alleviated pain ( < 0.01), but Recove showed more effectiveness (=0.01). Similarly, in terms of new blister formation, the experimental group receiving Recove showed less new blister formation over 24 hours after treatment compared to nitrofurazone group (=0.03) and with respect to antimicrobial activity, there was no significant difference between Recove and nitrofurazone (=0.12).
Recove was effective on pain reduction, prevention of new blisters formation as well as infection. Therefore, it seems that Recove could be considered as a new and efficient treatment for burn.
烧伤是所有社会面临的主要健康挑战之一，与其他任何创伤相比，给患者和社会带来了身体、心理、社会和经济负担。本研究旨在评估Recove烧伤软膏是否能够减轻疼痛、预防新水泡形成并控制伤口的微生物污染。
因此，我们将其疗效与%乳膏进行了比较。这项随机临床试验于2016年6月至10月在德黑兰省Motahari烧伤医院对身体同时有两处烧伤的个体进行。采用非随机方法利用现有样本进行抽样。实验组和对照组的干预分别为Recove和。评估了干预措施对减轻疼痛、新水泡形成以及烧伤创面感染预防的效果。在我们的双盲研究中，对患者和评估结果的人员实施了盲法。
Recove和呋喃西林干预均能显著减轻疼痛（<0.01），但Recove显示出更高的有效性（=0.01）。同样，在新水泡形成方面，接受Recove的实验组在治疗后24小时内新水泡形成少于呋喃西林组（=0.03），而就抗菌活性而言，Recove和呋喃西林之间无显著差异（=0.12）。
Recove在减轻疼痛、预防新水泡形成以及感染方面均有效。因此，Recove似乎可被视为一种新的高效烧伤治疗方法。
