Succi G, Pedrycz W, Bogachuk A P, Tormasov A G, Belogurov A A, Spallone A
Innopolis University, Innopolis, 420500 Russia.
University of Alberta, Edmonton (AB), T6G 2R3 Canada.
Acta Naturae. 2022 Oct-Dec;14(4):101-110. doi: 10.32607/actanaturae.11754.
The coronavirus D-19 (Covid-19) pandemic has shaken almost every country in the world: as we stand, 6,3 million deaths from the infection have already been recorded, 167,000 and 380,000 of which are in Italy and the Russian Federation, respectively. In the first wave of the pandemic, Italy suffered an abnormally high death toll. A detailed analysis of available epidemiological data suggests that that rate was shockingly high in the Northern regions and in Lombardy, in particular, whilst in the southern region the situation was less dire. This inexplicably high mortality rate in conditions of a very well-developed health care system such as the one in Lombardy - recognized as one of the best in Italy - certainly cries for a convincing explanation. In 1976, the small city of Seveso, Lombardy, experienced a release of dioxin into the atmosphere after a massive technogenic accident. The immediate effects of the industrial disaster did not become apparent until a surge in the number of tumors in the affected population in the subsequent years. In this paper, we endeavor to prove our hypothesis that the release of dioxin was a negative cofactor that contributed to a worsening of the clinical course of COVID-19 in Lombardy.
新型冠状病毒肺炎（COVID-19）大流行几乎震动了世界上的每个国家：截至目前，该感染已导致630万人死亡，其中意大利和俄罗斯联邦分别有16.7万和38万人死亡。在大流行的第一波中，意大利的死亡人数异常之高。对现有流行病学数据的详细分析表明，北部地区，尤其是伦巴第大区的死亡率高得惊人，而南部地区的情况则没那么严峻。在伦巴第大区这样一个医疗保健系统非常发达——被公认为意大利最好的之一——的情况下，出现如此高得离谱的死亡率，无疑需要一个令人信服的解释。1976年，伦巴第大区的小城塞韦索在一场重大技术事故后发生了二噁英向大气中的泄漏。这场工业灾难的直接影响直到随后几年受影响人群中的肿瘤数量激增才显现出来。在本文中，我们力图证明我们的假设，即二噁英的泄漏是一个负面辅助因素，导致伦巴第大区COVID-19临床病程恶化。
