2022 年 6 月，法国发现一株新型嵌合基因、对头孢曲松耐药、多种药物耐药的淋病奈瑟菌。
Ceftriaxone-resistant, multidrug-resistant with a novel mosaic gene, France, June 2022.
机构信息
French National Reference Centre for bacterial STIs, Associated Laboratory for Gonococci, Paris, France.
APHP, Infectious Agents Department, Saint Louis Hospital, Paris, France.
出版信息
Euro Surveill. 2022 Dec;27(50). doi: 10.2807/1560-7917.ES.2022.27.50.2200899.
We report a ceftriaxone-resistant, multidrug-resistant urogenital gonorrhoea case in a heterosexual woman in France, June 2022. The woman was successfully treated with azithromycin 2 g. She had unprotected sex with her regular partner, who developed urethritis following travel to Vietnam and Switzerland. Whole genome sequencing of the gonococcal isolate (F92) identified MLST ST1901, NG-STAR CC-199, and the novel mosaic , which caused ceftriaxone resistance. is 98.7% identical to , reported in various ceftriaxone-resistant strains, including the internationally spreading FC428 clone.
我们报告了 2022 年 6 月法国一名异性恋女性感染头孢曲松耐药、多种药物耐药的泌尿生殖道淋病病例。该女性成功接受了阿奇霉素 2g 治疗。她与性伴侣发生了无保护性行为，性伴侣在前往越南和瑞士旅行后出现了尿道炎。淋球菌分离株（F92）的全基因组测序鉴定出 MLST ST1901、NG-STAR CC-199 和新型马赛克 ，导致头孢曲松耐药。 与不同头孢曲松耐药株（包括国际传播的 FC428 克隆）中报告的 高度同源，相似度为 98.7%。
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