Collaborations Pharmaceuticals, Inc., 840 Main Campus Drive, Lab 3510, Raleigh, North Carolina 27606, United States.
Department of War Studies and Department of Global Health & Social Medicine, King's College London, Strand, London WC2R 2LS, United Kingdom.
J Chem Inf Model. 2023 Feb 13;63(3):691-694. doi: 10.1021/acs.jcim.2c01616. Epub 2023 Jan 25.
We have previously applied our machine learning models for bioactivity and toxicity along with a generative algorithm to develop VX and tens of thousands of analogues. The publication brought attention to the ease of designing chemical warfare agents. In this Viewpoint, we discuss 10 recommendations to prevent future biochemical threats.
我们之前应用机器学习模型进行生物活性和毒性研究,并结合生成算法来开发 VX 及数以万计的类似物。该出版物引起了人们对设计化学战剂的容易程度的关注。在本观点中,我们讨论了 10 项防止未来生化威胁的建议。