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用于注意力缺陷多动障碍的家庭式脑机接口注意力训练项目:一项可行性试验

Home-based brain-computer interface attention training program for attention deficit hyperactivity disorder: a feasibility trial.

作者信息

Lim Choon Guan, Soh Chui Pin, Lim Shernice Shi Yun, Fung Daniel Shuen Sheng, Guan Cuntai, Lee Tih-Shih

机构信息

Department of Developmental Psychiatry, Institute of Mental Health, 10, Buangkok View, Singapore, 539747, Singapore.

School of Computer Science and Engineering, Nanyang Technological University, Singapore, Singapore.

出版信息

Child Adolesc Psychiatry Ment Health. 2023 Jan 25;17(1):15. doi: 10.1186/s13034-022-00539-x.

Abstract

BACKGROUND

Attention deficit hyperactivity disorder (ADHD) is a prevalent child neurodevelopmental disorder that is treated in clinics and in schools. Previous trials suggested that our brain-computer interface (BCI)-based attention training program could improve ADHD symptoms. We have since developed a tablet version of the training program which can be paired with wireless EEG headsets. In this trial, we investigated the feasibility of delivering this tablet-based BCI intervention at home.

METHODS

Twenty children diagnosed with ADHD, who did not receive any medication for the preceding month, were randomised to receive the 8-week tablet-based BCI intervention either in the clinic or at home. Those in the home intervention group received instructions before commencing the program and got reminders if they were lagging on the training sessions. The ADHD Rating Scale was completed by a blinded clinician at baseline and at week 8. Adverse events were monitored during any contact with the child throughout the trial and at week 8.

RESULTS

Children in both groups could complete the tablet-based intervention easily on their own with minimal support from the clinic therapist or their parents (at home). The intervention was safe with few reported adverse effects. Clinician-rated inattentive symptoms on the ADHD-Rating Scale reduced by 3.2 (SD 6.20) and 3.9 (SD 5.08) for the home-based and clinic-based groups respectively, suggesting that home-based intervention was comparable to clinic-based intervention.

CONCLUSIONS

This trial demonstrated that the tablet version of our BCI-based attention training program can be safely delivered to children in the comfort of their own home. Trial registration This trial is registered at clinicaltrials.gov as NCT01344044.

摘要

背景

注意缺陷多动障碍(ADHD)是一种常见的儿童神经发育障碍,在诊所和学校都有相应治疗。先前的试验表明,我们基于脑机接口(BCI)的注意力训练项目可以改善ADHD症状。此后,我们开发了该训练项目的平板电脑版本,它可以与无线脑电图耳机配合使用。在本试验中,我们研究了在家中提供这种基于平板电脑的BCI干预措施的可行性。

方法

20名被诊断为ADHD的儿童,在之前一个月未接受任何药物治疗,被随机分为两组,分别在诊所或家中接受为期8周的基于平板电脑的BCI干预。在家中干预组的儿童在开始项目前接受指导,如果他们在训练课程上落后会收到提醒。ADHD评定量表由一位不知情的临床医生在基线和第8周时完成。在整个试验期间以及第8周与儿童的任何接触中监测不良事件。

结果

两组儿童都可以在诊所治疗师或其父母(在家中)的最少支持下轻松自行完成基于平板电脑的干预。该干预措施安全,报告的不良反应很少。ADHD评定量表上临床医生评定的注意力不集中症状,在家中干预组和诊所干预组分别减少了3.2(标准差6.20)和3.9(标准差5.08),这表明在家中进行的干预与在诊所进行的干预效果相当。

结论

本试验表明,我们基于BCI的注意力训练项目的平板电脑版本可以在儿童自己家中安全地提供给他们。试验注册 本试验在clinicaltrials.gov上注册,注册号为NCT01344044。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21bc/9878772/9f46b04f5245/13034_2022_539_Fig1_HTML.jpg

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