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阿片类药物使用障碍源于罂粟籽茶的使用:病例报告。

Opioid Use Disorder from Poppy Seed Tea Use: A Case Report.

机构信息

Department of Family Medicine, Mayo Clinic Health System, Eau Claire, WI, USA.

Department of Family Medicine and Community Health, University of Wisconsin - Madison, Madison, WI, USA.

出版信息

Am J Case Rep. 2023 Jan 26;24:e938675. doi: 10.12659/AJCR.938675.

DOI:10.12659/AJCR.938675
PMID:36698302
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9887487/
Abstract

BACKGROUND Unwashed or unprocessed poppy seeds may be an underrecognized substance that can lead to dependence, abuse, and an opioid use disorder. Poppy seeds can be purchased in an unwashed or unprocessed form, and these seeds can be contaminated with the opium alkaloids morphine, codeine, and thebaine on their surfaces. Poppy seeds that are commercially available, such as those used for baking and in other food products, are legal to purchase, as they do not contain the opium alkaloids on their seed coats. Purchase and possession of the unwashed or unprocessed seeds are not legal in the United States. These contaminated poppy seeds can then be put through a process in which they are washed, and the supernatant (tea) is collected and consumed to experience its intoxicating effect or for the treatment of pain or opioid withdrawal. CASE REPORT A 65-year-old man with a history of alcohol use disorder, cannabis use, and chronic pain began using this poppy seed tea for treatment of chronic pain after his provider had stopped prescribing opioid pain medications for him. He developed a dependence on the tea. He had reached out for assistance as it was his desire to stop using the poppy seed tea. The diagnosis of an opioid use disorder was made using the DSM-V criteria. He was successfully induced and maintained on a buprenorphine/naloxone product. CONCLUSIONS Poppy seeds in their unwashed and unprocessed form can be misused and could lead to an opioid use disorder. This disorder can be treated with buprenorphine/naloxone products.

摘要

背景

未清洗或未经加工的罂粟籽可能是一种被低估的物质,可导致依赖、滥用和阿片类药物使用障碍。罂粟籽可未经清洗或加工购买,这些种子表面可能会被鸦片生物碱吗啡、可待因和蒂巴因污染。可商业购买的罂粟籽,如用于烘焙和其他食品产品的罂粟籽,其种皮不含有鸦片生物碱,因此购买和持有是合法的。在美国,未经清洗或未经加工的种子的购买和持有是不合法的。然后,这些受污染的罂粟籽可以经过清洗过程,收集上清液(茶)并饮用,以体验其致醉效果,或用于治疗疼痛或阿片类药物戒断。

病例报告

一名 65 岁男子,有酒精使用障碍、大麻使用和慢性疼痛病史,在其医生停止为他开阿片类止痛药后,开始使用这种罂粟籽茶来治疗慢性疼痛。他对这种茶产生了依赖。他已经寻求帮助,因为他希望停止使用罂粟籽茶。根据 DSM-V 标准,诊断为阿片类药物使用障碍。他成功地接受并维持使用丁丙诺啡/纳洛酮产品。

结论

未经清洗或未经加工的罂粟籽可能被滥用,并可能导致阿片类药物使用障碍。这种疾病可以用丁丙诺啡/纳洛酮产品治疗。

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Opioid Use Disorder from Poppy Seed Tea Use: A Case Report.阿片类药物使用障碍源于罂粟籽茶的使用:病例报告。
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本文引用的文献

1
Maternal Poppy Seed Tea Ingestion and Ensuing Neonatal Abstinence Syndrome.母亲饮用罂粟籽茶与新生儿戒断综合征。
Neonatology. 2020;117(4):529-531. doi: 10.1159/000508446. Epub 2020 Jul 6.
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Poppy seed tea and opiate abuse in New Zealand.
Drug Alcohol Rev. 2007 Mar;26(2):215-9. doi: 10.1080/09595230601146637.
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The determination of morphine in urine and oral fluid following ingestion of poppy seeds.食用罂粟籽后尿液和口腔液中吗啡的测定。
J Anal Toxicol. 2003 Oct;27(7):449-52. doi: 10.1093/jat/27.7.449.