Gordon Brett R, Qiu Ling, Doerksen Shawna E, Kanski Bethany, Lorenzo Abigail, Truica Cristina I, Vasekar Monali, Wang Ming, Winkels Renate M, Abdullah Saeed, Schmitz Kathryn H
Pennylvania State University College of Medicine, Hershey, PA, USA.
Pennsylvania State University College of Information and Science Technology, University Park, PA, USA.
Contemp Clin Trials Commun. 2023 Jan 16;32:101058. doi: 10.1016/j.conctc.2023.101058. eCollection 2023 Apr.
Metastatic Breast Cancer (MBC) patients often feel their symptom-related needs are unmet, despite visiting their doctors up to once a week. Novel approaches are needed to address symptoms without requiring additional appointments. Technology based symptom management approaches to address symptoms have not been well tested.
Nurse AMIE (Addressing Metastatic Individuals Everyday) is a technology based supportive care platform that provides guideline-concordant symptom management interventions in response to patient reported symptoms. We have previously successfully implemented a tablet version of Nurse AMIE. However, some eligible patients chose not to participate because they were overwhelmed by the technology. To address this barrier, we translated the Nurse AMIE platform to the Amazon Echo Show, which allowed for voice-based interactions. Forty-two MBC patients were randomized 1:1 to receive the Nurse AMIE for Echo Show immediately for six months, or to receive the same intervention for three months, after a three month delay. The primary outcome was change in physical distress over three months, and secondary outcomes included feasibility, acceptability, patient reported outcomes and usability.
Results from the Nurse AMIE for Echo Show trial will identify the feasibility, acceptability, and preliminary effects of the Nurse AMIE for Echo Show on patient reported outcomes. Untested novel technologies, particularly voice-based artificial intelligence devices may an effective and scalable vehicle through which we can deliver supportive care interventions.
NCT04673019.
转移性乳腺癌（MBC）患者尽管每周就医一次，但仍常觉得其症状相关需求未得到满足。需要新方法来解决症状问题，且无需额外预约。基于技术的症状管理方法在解决症状方面尚未得到充分测试。
护士AMIE（每日关怀转移性患者）是一个基于技术的支持性护理平台，可根据患者报告的症状提供符合指南的症状管理干预措施。我们之前已成功实施了护士AMIE的平板电脑版本。然而，一些符合条件的患者选择不参与，因为他们被技术弄得不知所措。为解决这一障碍，我们将护士AMIE平台移植到了亚马逊Echo Show上，这实现了基于语音的交互。42名MBC患者按1:1随机分组，一组立即接受针对Echo Show的护士AMIE干预六个月，另一组在延迟三个月后接受相同干预三个月。主要结局是三个月内身体痛苦的变化，次要结局包括可行性、可接受性、患者报告的结局和可用性。
针对Echo Show的护士AMIE试验结果将确定其在患者报告结局方面的可行性、可接受性和初步效果。未经测试的新技术，尤其是基于语音的人工智能设备，可能是一种有效且可扩展的载体，通过它我们可以提供支持性护理干预措施。
NCT04673019。
