Suppr超能文献

下颌下腺嗜酸性细胞瘤:罕见肿瘤病例系列——基于临床病理学的诊断与治疗

Submandibular Gland Oncocytoma: A Rare Tumor Case Series-Its Diagnosis and Treatment Based on Clinicopathology.

作者信息

Bhushan Lt Col Kritant

机构信息

Armed force hospital, Gangtok, India.

出版信息

J Maxillofac Oral Surg. 2023 Mar;22(1):127-131. doi: 10.1007/s12663-022-01775-6. Epub 2022 Aug 8.

Abstract

AIM AND OBJECTIVE

Submandibular oncocytomas are rare benign salivary gland neoplasms, normally involves the parotid gland and few instances are stated in the submandibular gland region. As the clinical and histopathological features are overlapping to another salivary gland tumor like pleomorphic adenoma or warthin tumour, they are often misdiagnosed. They are typically found in patients aged 50-70 years with no gender preference. The aim of this paper is to assess the clinicopathological functions, diagnostic standards and treatment of submandibular gland oncocytomas via a series of three case reports.

METHOD AND RESULTS

We report a three case series of unilateral submandibular gland oncocytoma with female to male ratio 2:1, Size of tumor ranged from 1.8 to 10 cm, 2 cases have painless swelling and one involved tender mass. FNAC and CT scan confirmed the presence of an oncocytoma. The patient underwent unilateral submandibular gland resection and on follow up no evidence of any recurrence was identified.

CONCLUSION

Submandibular oncocytomas often present as solitary slow growing painless masses, which are firm on clinical examination. CT followed by fine-needle aspiration cytology (FNAC) would be the preferred diagnostic modalities. Due to its low rate of malignant transformation and recurrence, the best treatment is local resection with follow-up as necessary.

摘要

目的与目标

下颌下腺嗜酸性细胞瘤是罕见的良性涎腺肿瘤,通常累及腮腺,仅有少数病例发生于下颌下腺区域。由于其临床和组织病理学特征与多形性腺瘤或沃辛瘤等其他涎腺肿瘤重叠,常被误诊。它们通常见于50至70岁的患者,无性别差异。本文旨在通过一系列三例病例报告评估下颌下腺嗜酸性细胞瘤的临床病理特征、诊断标准及治疗方法。

方法与结果

我们报告了一组三例单侧下颌下腺嗜酸性细胞瘤病例,男女比例为2:1,肿瘤大小为1.8至10厘米,2例有无痛性肿胀,1例伴有压痛性肿块。细针穿刺抽吸活检(FNAC)和CT扫描确诊为嗜酸性细胞瘤。患者接受了单侧下颌下腺切除术,随访未发现复发迹象。

结论

下颌下腺嗜酸性细胞瘤常表现为孤立性、生长缓慢的无痛性肿块,临床检查质地坚硬。CT检查后行细针穿刺抽吸细胞学检查(FNAC)是首选的诊断方法。由于其恶变和复发率低,最佳治疗方法是局部切除并根据需要进行随访。

相似文献

1
Submandibular Gland Oncocytoma: A Rare Tumor Case Series-Its Diagnosis and Treatment Based on Clinicopathology.
J Maxillofac Oral Surg. 2023 Mar;22(1):127-131. doi: 10.1007/s12663-022-01775-6. Epub 2022 Aug 8.
2
Oncocytoma of the Submandibular Gland: Diagnosis and Treatment Based on Clinicopathology.
Case Rep Otolaryngol. 2016;2016:8719030. doi: 10.1155/2016/8719030. Epub 2016 Sep 19.
6
Pleomorphic Adenoma of the Submandibular Gland: A Case Report.
JNMA J Nepal Med Assoc. 2019 Jan-Feb;57(215):53-55. doi: 10.31729/jnma.4001.
7
Submandibular gland pleomorphic adenoma in a seven-year-old child: a case report.
Kulak Burun Bogaz Ihtis Derg. 2010 Jul-Aug;20(4):210-3.
8
Fine-needle aspiration cytology: a reliable tool in the diagnosis of salivary gland lesions.
J Oral Pathol Med. 2012 Jan;41(1):106-12. doi: 10.1111/j.1600-0714.2011.01069.x. Epub 2011 Aug 29.
9
[Diagnostic value of fine needle aspiration cytology in salivary gland masses].
Kulak Burun Bogaz Ihtis Derg. 2009 Mar-Apr;19(2):71-6.
10
Pleomorphic Adenoma of the Submandibular Gland in a 10-Year-Old Child: A Case Report.
Ear Nose Throat J. 2023 Nov;102(11):NP552-NP555. doi: 10.1177/01455613211022113. Epub 2021 Jul 8.

引用本文的文献

1
Salivary Gland Oncocytomas. A Systematic Review.
Head Neck Pathol. 2024 Nov 30;18(1):126. doi: 10.1007/s12105-024-01730-6.
2
Case of clear-cell oncocytoma of parotid gland and literature review.
Hua Xi Kou Qiang Yi Xue Za Zhi. 2024 Feb 1;42(1):126-134. doi: 10.7518/hxkq.2024.2023185.

本文引用的文献

1
Metastasising pleomorphic adenoma: Systematic review.
Int J Surg. 2015 Jul;19:137-45. doi: 10.1016/j.ijsu.2015.04.084. Epub 2015 May 6.
2
Squamous carcinoma arising in a parotid Warthin's tumour.
BMJ Case Rep. 2014 Dec 12;2014:bcr2014207870. doi: 10.1136/bcr-2014-207870.
3
Solitary oncocytoma of the submandibular salivary gland in an adolescent female: A case report.
Indian J Otolaryngol Head Neck Surg. 2007 Jun;59(2):171-3. doi: 10.1007/s12070-007-0051-0. Epub 2007 Sep 14.
4
Bilateral submandibular gland oncocytoma in a patient with multiple endocrine neoplasia 2B syndrome and neurofibromatosis type 1: an unusual case.
Int J Oral Maxillofac Surg. 2011 Jul;40(7):764-7. doi: 10.1016/j.ijom.2011.02.017. Epub 2011 Mar 17.
5
Malignant transformation of a benign oncocytoma of the submandibular gland: a case report.
Kaohsiung J Med Sci. 2010 Jun;26(6):327-32. doi: 10.1016/S1607-551X(10)70047-4.
6
Primary tumors of the submandibular glands: a retrospective study based on 41 cases.
Oral Oncol. 2010 Apr;46(4):287-91. doi: 10.1016/j.oraloncology.2010.01.011. Epub 2010 Feb 26.
7
Fine needle aspiration cytology of oncocytic carcinoma of the submandibular gland with pre-existing oncocytoma: a case report.
Cytopathology. 2010 Oct;21(5):339-41. doi: 10.1111/j.1365-2303.2009.00720.x. Epub 2009 Dec 3.
8
F-18 FDG PET/CT imaging of submandibular gland oncocytoma.
Clin Nucl Med. 2008 Jul;33(7):472-4. doi: 10.1097/RLU.0b013e31817792b6.
10
Submaxillary oncocytoma. Oxyphil-cell adenoma.
Arch Otolaryngol. 1961 Sep;74:299-301. doi: 10.1001/archotol.1961.00740030306011.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验