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微藻生物技术的炒作、希望与前进之路。

Hypes, hopes, and the way forward for microalgal biotechnology.

机构信息

Bioprocess Engineering & AlgaePARC, Wageningen University and Research, PO Box 16, Wageningen, 6700, AA, The Netherlands.

Bioprocess Engineering & AlgaePARC, Wageningen University and Research, PO Box 16, Wageningen, 6700, AA, The Netherlands.

出版信息

Trends Biotechnol. 2023 Mar;41(3):452-471. doi: 10.1016/j.tibtech.2022.12.017. Epub 2023 Jan 25.

DOI:10.1016/j.tibtech.2022.12.017
PMID:36707271
Abstract

The urge for food security and sustainability has advanced the field of microalgal biotechnology. Microalgae are microorganisms able to grow using (sun)light, fertilizers, sugars, CO, and seawater. They have high potential as a feedstock for food, feed, energy, and chemicals. Microalgae grow faster and have higher areal productivity than plant crops, without competing for agricultural land and with 100% efficiency uptake of fertilizers. In comparison with bacterial, fungal, and yeast single-cell protein production, based on hydrogen or sugar, microalgae show higher land-use efficiency. New insights are provided regarding the potential of microalgae replacing soy protein, fish oil, and palm oil and being used as cell factories in modern industrial biotechnology to produce designer feed, recombinant proteins, biopharmaceuticals, and vaccines.

摘要

对食品安全和可持续性的需求推动了微藻生物技术领域的发展。微藻是能够利用(太阳)光、肥料、糖、CO 和海水生长的微生物。它们具有作为食品、饲料、能源和化学品原料的巨大潜力。微藻的生长速度比植物作物快,单位面积的生产力更高,而且不会与农业用地竞争,肥料的吸收率达到 100%。与基于氢气或糖的细菌、真菌和酵母单细胞蛋白生产相比,微藻显示出更高的土地利用效率。文中提供了关于微藻替代大豆蛋白、鱼油和棕榈油的潜力的新见解,并将其用作现代工业生物技术中的细胞工厂,以生产设计饲料、重组蛋白、生物制药和疫苗。

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