School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing 210023, People's Republic of China.
School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing 210023, People's Republic of China.
Trends Biotechnol. 2023 Jul;41(7):857-859. doi: 10.1016/j.tibtech.2023.01.001. Epub 2023 Jan 26.
Polyunsaturated fatty acids (PUFAs) are important nutrients for humans and animals. Microorganisms, such as yeast, filamentous fungi, and microalgae, have successfully been modified to produce PUFAs. Apart from strain improvement and fermentation optimization, efficient and cost-effective downstream processing will determine whether production can advance from the laboratory to the factory.
多不饱和脂肪酸(PUFAs)是人类和动物的重要营养物质。酵母、丝状真菌和微藻等微生物已成功被改造以生产 PUFAs。除了菌株改良和发酵优化之外,高效且经济有效的下游加工将决定生产能否从实验室推进到工厂。