Ji Xiao-Jun, Ledesma-Amaro Rodrigo
College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, No. 30 South Puzhu Road, Nanjing 211816, People's Republic of China.
Department of Bioengineering and Imperial College Centre for Synthetic Biology, Imperial College London, London, SW7 2AZ, UK.
Trends Biotechnol. 2020 Aug;38(8):832-834. doi: 10.1016/j.tibtech.2020.02.003. Epub 2020 Mar 2.
Lipids rich in polyunsaturated fatty acids are important nutrients. They are traditionally extracted from animals and plants but alternatively can be obtained from microbes through microbial lipid biotechnology. To make this process more economical, apart from strain engineering, the next frontier is through bioprocess and downstream innovation.
富含多不饱和脂肪酸的脂质是重要的营养物质。传统上它们是从动植物中提取的,但也可以通过微生物脂质生物技术从微生物中获得。为了使这个过程更经济,除了菌株工程,下一个前沿领域是生物工艺和下游创新。