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书面哮喘行动计划改善马来西亚小儿哮喘患者的哮喘控制和生活质量:一项随机对照试验。

Written Asthma Action Plan Improves Asthma Control and the Quality of Life among Pediatric Asthma Patients in Malaysia: A Randomized Control Trial.

作者信息

Muhammad Juliawati, Ngah Najwa Diyana, Ahmad Imran

机构信息

Department of Family Medicine, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Malaysia.

Department of Family Medicine, Klinik Kesihatan Ketengah, Ketengah Jaya, Malaysia.

出版信息

Korean J Fam Med. 2023 Jan;44(1):44-52. doi: 10.4082/kjfm.22.0016. Epub 2023 Jan 19.

Abstract

BACKGROUND

A written asthma action plan (WAAP) is one of the treatment strategies to achieve good asthma control in children.

METHODS

This randomized controlled trial was conducted to observe the effect of WAAP on asthma control and quality of life using the Asthma Control Questionnaire and Pediatric Asthma Quality of Life Questionnaire (PAQLQ) at baseline and after 3 months. A repeated measure analysis of variance was used to analyze the mean score difference between the two groups.

RESULTS

There was no significant difference in mean score for asthma control at baseline between groups (F[degree of freedom (df)]=1.17 [1, 119], P=0.282). However, at 3 months, a significant difference in mean scores between groups was observed (F[df]=7.32 [1, 119], P=0.008). The mean±standard deviation (SD) scores in the intervention and control groups were 0.96±0.53 and 1.21±0.49, respectively. For the analysis of the PAQLQ, no significant difference was observed in the mean score for the quality of life baseline in both groups. There were significant mean score changes for the quality of life (F[df]=10.9 [1, 119], P=0.001) at 3 months follow-up, where those in the intervention group scored a mean±SD score of 6.19±0.45, and those in the control group scored 5.94±0.38. A time-group interaction analysis using repeated-measures analysis of variance showed significant differences in mean score changes (F[df]=5.03 [1, 116], P=0.027) and (F[df]=11.55 [1, 116], P=0.001) where a lower mean score was observed in the intervention group, indicating better asthma control and quality of life, respectively. A significant (P<0.001) negative Pearson correlation between asthma control and quality of life (-0.65) indicated a moderate correlation.

CONCLUSION

WAAP, along with standard asthma treatment, improves asthma care.

摘要

背景

书面哮喘行动计划(WAAP)是实现儿童哮喘良好控制的治疗策略之一。

方法

本随机对照试验旨在使用哮喘控制问卷和儿童哮喘生活质量问卷(PAQLQ)在基线及3个月后观察WAAP对哮喘控制和生活质量的影响。采用重复测量方差分析来分析两组之间的平均得分差异。

结果

两组在基线时哮喘控制的平均得分无显著差异(F[自由度(df)]=1.17 [1, 119],P = 0.282)。然而,在3个月时,观察到两组之间的平均得分有显著差异(F[df]=7.32 [1, 119],P = 0.008)。干预组和对照组的平均±标准差(SD)得分分别为0.96±0.53和1.21±0.49。对于PAQLQ的分析,两组在生活质量基线的平均得分无显著差异。在3个月随访时,生活质量有显著的平均得分变化(F[df]=10.9 [1, 119],P = 0.001),其中干预组的平均±SD得分为6.19±0.45,对照组为5.94±0.38。使用重复测量方差分析的时间 - 组交互分析显示平均得分变化有显著差异(F[df]=5.03 [1, 116],P = 0.027)和(F[df]=11.55 [1, 116],P = 0.001),其中干预组的平均得分较低,分别表明哮喘控制更好和生活质量更高。哮喘控制与生活质量之间存在显著的(P < 0.001)负Pearson相关性(-0.65),表明存在中度相关性。

结论

WAAP与标准哮喘治疗一起可改善哮喘护理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14d9/9887449/4beef62762f8/kjfm-22-0016f1.jpg

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