Ferro Desideri Lorenzo, Rosa Raffaella, Forte Paolo, Manocchio Riccardo, Vagge Aldo, Traverso Carlo Enrico, Nicolò Massimo
IRCCS Ospedale Policlinico San Martino, University Eye Clinic of Genoa, Genoa, Italy.
Dipartimento di Neuroscienze, riabilitazione, oftalmologia, genetica e scienze materno-infantili (DINOGMI), Università di Genova, Genova, Italy.
Eur J Ophthalmol. 2023 Nov;33(6):NP58-NP64. doi: 10.1177/11206721231154172. Epub 2023 Jan 29.
Lyme borreliosis may present with different systemic manifestations and also the ocular involvement may be difficult to diagnose because of its multifaceted presentation. Considering the growing incidence of Lyme disease in European countries, ophthalmologist should be trained to distinguish ocular borreliosis.
Several clinical presentations have been previously described, including uveitis, unilateral or bilateral chorioretinitis, keratitis, episcleritis, papillitis and ischemic optic neuropathy, retinal vasculitis and acute posterior multifocal placoid pigment epitheliopathy (APMPPE); however our case report showed a rare presentation with the presence of unilateral uveitis with vitreitis and multiple, patchy, yellowish lesions, in association with retinal vasculitis. This clinical picture was to be considered in differential diagnosis with ocular Toxoplasmosis.
The appropriate management of this patient was made possible by the combination of multimodal imaging and appropriate laboratory tests, representing the optimal process in the diagnostic and therapeutic pathway in high-risk patients for ocular Lyme disease.
莱姆病可能表现出不同的全身症状,而且由于其表现形式多样,眼部受累可能难以诊断。鉴于欧洲国家莱姆病发病率不断上升,眼科医生应接受培训以鉴别眼部莱姆病。
此前已描述过多种临床表现,包括葡萄膜炎、单侧或双侧脉络膜视网膜炎、角膜炎、巩膜炎、视乳头炎、缺血性视神经病变、视网膜血管炎以及急性后极部多灶性鳞状色素上皮病变(APMPPE);然而我们的病例报告显示了一种罕见表现,即单侧葡萄膜炎合并玻璃体炎以及多个片状淡黄色病变,并伴有视网膜血管炎。在与眼部弓形虫病的鉴别诊断中应考虑到这种临床症状。
通过多模态成像和适当的实验室检查相结合,对该患者进行了恰当的治疗,这代表了眼部莱姆病高危患者诊断和治疗途径中的最佳流程。