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葡萄膜炎的病因:感染的作用,特别提及莱姆病。

The etiology of uveitis: the role of infections with special reference to Lyme borreliosis.

作者信息

Mikkilä H, Seppälä I, Leirisalo-Repo M, Immonen I, Karma A

机构信息

Department of Ophthalmology, University of Helsinki, Finland.

出版信息

Acta Ophthalmol Scand. 1997 Dec;75(6):716-9. doi: 10.1111/j.1600-0420.1997.tb00637.x.

DOI:10.1111/j.1600-0420.1997.tb00637.x
PMID:9527338
Abstract

PURPOSE

To assess the distribution of different uveitis entities and to evaluate their associations with infections, especially Lyme borreliosis.

METHODS

During a one-year period 160 consecutive uveitis patients were evaluated in a university clinic. Selected tests were performed depending on the medical history of the patient and the clinical picture of the ocular inflammation.

RESULTS

Uveitis was classified into selected entities for 74.4% of the patients. A direct infection was suggested to be linked with uveitis in 23 patients (14.4%). Lyme borreliosis, toxoplasmosis, and herpetic infections were the most frequently seen, in seven patients (4.3%) each. All patients with Lyme uveitis had manifestations of the posterior segment of the eye, such as vitritis, retinal vasculitis, neuroretinitis, chorioretinitis, or optic neuropathy.

CONCLUSION

Infections are an important cause of uveitis in a university clinic. Lyme borreliosis is a newly recognised uveitis entity which should be kept in mind in the differential diagnosis of intermediate or posterior uveitis in areas endemic for Lyme borreliosis.

摘要

目的

评估不同葡萄膜炎类型的分布情况,并评估它们与感染尤其是莱姆病的关联。

方法

在一年时间里,一所大学诊所对160例连续性葡萄膜炎患者进行了评估。根据患者的病史和眼部炎症的临床表现进行了特定检查。

结果

74.4%的患者的葡萄膜炎被分类为特定类型。23例患者(14.4%)的葡萄膜炎被认为与直接感染有关。莱姆病、弓形虫病和疱疹感染最为常见,各有7例患者(4.3%)。所有莱姆病性葡萄膜炎患者均有眼后段表现,如玻璃体炎、视网膜血管炎、神经视网膜炎、脉络膜视网膜炎或视神经病变。

结论

在大学诊所中,感染是葡萄膜炎的一个重要病因。莱姆病是一种新认识的葡萄膜炎类型,在莱姆病流行地区,对中间或后葡萄膜炎进行鉴别诊断时应予以考虑。

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