Croon P M, Selder J L, Allaart C P, Bleijendaal H, Chamuleau S A J, Hofstra L, Išgum I, Ziesemer K A, Winter M M
Heart Center, Department of Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Department of Clinical Epidemiology, Biostatistics & Bioinformatics, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands.
Eur Heart J Digit Health. 2022 Jun 24;3(3):415-425. doi: 10.1093/ehjdh/ztac035. eCollection 2022 Sep.
Patients with congestive heart failure (HF) are prone to clinical deterioration leading to hospital admissions, burdening both patients and the healthcare system. Predicting hospital admission in this patient group could enable timely intervention, with subsequent reduction of these admissions. To date, hospital admission prediction remains challenging. Increasing amounts of acquired data and development of artificial intelligence (AI) technology allow for the creation of reliable hospital prediction algorithms for HF patients. This scoping review describes the current literature on strategies and performance of AI-based algorithms for prediction of hospital admission in patients with HF.
PubMed, EMBASE, and the Web of Science were used to search for articles using machine learning (ML) and deep learning methods to predict hospitalization in patients with HF. After eligibility screening, 23 articles were included. Sixteen articles predicted 30-day hospital (re-)admission resulting in an area under the curve (AUC) ranging from 0.61 to 0.79. Six studies predicted hospital admission over longer time periods ranging from 6 months to 3 years, with AUC's ranging from 0.65 to 0.78. One study prospectively evaluated performance of a disposable sensory patch at home after hospitalization which resulted in an AUC of 0.89 for unplanned hospital admission prediction.
AI has the potential to enable prediction of hospital admission in HF patients. Improvement of data management, adding new data sources such as telemonitoring data and ML models and prospective and external validation of current models must be performed before clinical applicability is possible.
充血性心力衰竭(HF)患者容易出现临床病情恶化,导致住院治疗,给患者和医疗系统都带来负担。预测该患者群体的住院情况能够实现及时干预,从而减少住院次数。迄今为止,住院预测仍然具有挑战性。获取的数据量不断增加以及人工智能(AI)技术的发展,使得为HF患者创建可靠的住院预测算法成为可能。本综述描述了关于基于AI的算法在预测HF患者住院方面的策略和性能的当前文献。
使用PubMed、EMBASE和科学网搜索使用机器学习(ML)和深度学习方法预测HF患者住院情况的文章。经过资格筛选,纳入了23篇文章。16篇文章预测了30天内的医院(再)入院情况,曲线下面积(AUC)范围为0.61至0.79。六项研究预测了6个月至3年的较长时间段内的住院情况,AUC范围为0.65至0.78。一项研究前瞻性评估了住院后在家中使用一次性传感贴片的性能,其对非计划住院预测的AUC为0.89。
AI有潜力实现对HF患者住院情况的预测。在实现临床适用性之前,必须改进数据管理,添加新的数据源,如远程监测数据和ML模型,并对当前模型进行前瞻性和外部验证。