Labib M, McPhate G, Marks V
Department of Clinical Biochemistry, St Luke's Hospital, Guildford, Surrey, UK.
Postgrad Med J. 1987 Jan;63(735):33-5. doi: 10.1136/pgmj.63.735.33.
We describe a case of diabetes insipidus after head injury in which thirst persisted despite treatment with DDAVP and normal plasma osmolality. Symptoms were only completely relieved when plasma osmolality was below 270 mosmol/kg. We believe that this might have been due to hypothalamic injury causing resetting of the thirst osmostat. To our knowledge, this type of primary polydipsia has not been described before in association with diabetes insipidus following head injury.
我们描述了一例头部受伤后发生尿崩症的病例，尽管使用去氨加压素治疗且血浆渗透压正常，但口渴症状仍持续存在。只有当血浆渗透压低于270毫摩尔/千克时，症状才完全缓解。我们认为这可能是由于下丘脑损伤导致口渴渗透压调定点重置。据我们所知，这种类型的原发性烦渴此前尚未被描述为与头部受伤后的尿崩症相关联。
