O'Neal Monica A, Gutierrez Nikko Rigor, Laing Kyla L, Manoogian Emily N C, Panda Satchidananda
Regulatory Biology Department, Salk Institute for Biological Studies, La Jolla, CA, United States.
Front Nutr. 2023 Jan 12;9:1075744. doi: 10.3389/fnut.2022.1075744. eCollection 2022.
Time-restricted eating (TRE) has shown potential benefits in optimizing the body's circadian rhythms and improving cardiometabolic health. However, as with all dietary interventions, a participant's ability to adhere to the protocol may be largely influenced by a variety of lifestyle factors. In TRE trials that reported participants' rates of adherence, the percentage of total days with successful adherence to TRE ranged from 47% to 95%. The purpose of this review is to (1) summarize findings of lifestyle factors affecting adherence to TRE clinical trials outside of the lab, and (2) explore a recommended set of behavioral intervention strategies for the application of TRE. A literature search on Pubmed was conducted to identify clinical TRE studies from 1988 to October 5, 2022, that investigated TRE as a dietary intervention. 21 studies included daily self-monitoring of adherence, though only 10 studies reported a combination of family, social, work, and miscellaneous barriers. To maximize participant adherence to TRE and increase the reliability of TRE clinical trials, future studies should monitor adherence, assess potential barriers, and consider incorporating a combination of behavioral intervention strategies in TRE protocols.
限时进食（TRE）已显示出在优化人体昼夜节律和改善心脏代谢健康方面的潜在益处。然而，与所有饮食干预措施一样，参与者遵守该方案的能力可能在很大程度上受到多种生活方式因素的影响。在报告参与者依从率的TRE试验中，成功坚持TRE的总天数百分比在47%至95%之间。本综述的目的是：（1）总结影响实验室外TRE临床试验依从性的生活方式因素的研究结果，以及（2）探索一套推荐的行为干预策略，以应用TRE。我们在PubMed上进行了文献检索，以确定1988年至2022年10月5日期间将TRE作为饮食干预措施进行研究的临床TRE研究。21项研究包括对依从性的每日自我监测，不过只有10项研究报告了家庭、社会、工作和其他方面的障碍。为了最大限度地提高参与者对TRE的依从性并提高TRE临床试验的可靠性，未来的研究应监测依从性，评估潜在障碍，并考虑在TRE方案中纳入多种行为干预策略的组合。
