Sakamoto Erica, Safatle-Ribeiro Adriana Vaz, Jr Ulysses Ribeiro
Department of Gastroenterology, Instituto do Cancer do Estado de São Paulo, Hospital das Clinicas, Faculdade de Medicina, Universidade de São Paulo, (ICESP-HCFMUSP) São Paulo, SP 01246-000, Brazil.
Chin J Cancer Res. 2022 Dec 30;34(6):587-591. doi: 10.21147/j.issn.1000-9604.2022.06.06.
Surgery is still the primary curative treatment for gastric cancer, which includes resection of the tumor with adequate margins and extended lymphadenectomy. In order to improve the operative results and the quality of life of patients, several endeavors have been made toward precision medicine through image-guided surgery, allowing access to real-time intraoperative anatomy and accurate tumor staging. The goal of the surgeon is to achieve a more precise, individualized, and less invasive surgery without compromising oncological efficiency and safety. In this perspective, we have demonstrated the role of indocyanine green (ICG) and near-infrared (NIR) fluorescence imaging method in gastric cancer surgery. This technique may be used to improve localization of the tumor, detection of sentinel lymph nodes (SLN), real-time lymphatic mapping, and blood flow assessment (anastomosis perfusion).
手术仍然是胃癌的主要治愈性治疗方法，包括切除具有足够切缘的肿瘤并进行扩大淋巴结清扫。为了提高手术效果和患者的生活质量，人们通过影像引导手术朝着精准医学方向做出了多项努力，这使得能够获取实时术中解剖结构并进行准确的肿瘤分期。外科医生的目标是在不影响肿瘤学疗效和安全性的前提下，实现更精确、个性化且侵入性更小的手术。从这个角度来看，我们已经证明了吲哚菁绿（ICG）和近红外（NIR）荧光成像方法在胃癌手术中的作用。该技术可用于改善肿瘤定位、前哨淋巴结（SLN）检测、实时淋巴绘图以及血流评估（吻合口灌注）。
