Cruz Marla S P, Reis Tercio G, Nunes Jackeline Sena, Oliveira Antoniel C, Teixeira Ágda Braga, Costa Karina Silva, Oliveira Márcio C
Departament of Public Health/Epidemiology, Universidade Estadual de Feira de Santana, Feira de Santana, Bahia, Brazil.
High Complexity Unit in Oncology of Feira de Santana, Feira de Santana, Bahia, Brazil.
Int Arch Otorhinolaryngol. 2022 Aug 1;27(1):e111-e116. doi: 10.1055/s-0042-1744168. eCollection 2023 Jan.
Head and neck cancer (HNC) and its treatment can cause physical, psychological, and quality of life (QoL) damage, because it can disturb the physiology of eating, breathing, speaking, and compromise self-image. To evaluate the QoL of the pretreatment of patients diagnosed with head and neck cancer according to the anatomical location of the tumor. A descriptive, cross-sectional study was performed on a sample of 144 patients undergoing pretreatment for cancer from February 2017 to July 2019. The University of Washington QoL Questionnaire (version 4) was used to assess the QoL. The anatomical location data were obtained from medical records. The ANOVA test was used to compare the differences in QoL according to tumor location. A total of 144 participants were included, 66 (45.5%) of whom had the primary tumor located in the mouth. The median age of the patients was 62 years, with a higher prevalence of male (75.7%), Black (78.5%), single/divorced/widowed people (59%), and illiterates (32.6%); most of them were smokers (84.7%) and alcohol drinkers (79.2%). The mean QoL score was 830 for mouth cancer, 858 for pharynx cancer, and 891 for laryngeal cancer patients. Based on the results of this study, it can be concluded that the QoL of patients with head and neck cancer was not influenced by tumor location. The most affected domains in the three groups were pain, appearance, chewing, swallowing, and speech ( < 0.05).
头颈癌（HNC）及其治疗会对身体、心理和生活质量（QoL）造成损害，因为它会干扰进食、呼吸、说话的生理功能，并损害自我形象。
为了根据肿瘤的解剖位置评估被诊断为头颈癌患者治疗前的生活质量。
对2017年2月至2019年7月期间144例接受癌症治疗前的患者样本进行了描述性横断面研究。使用华盛顿大学生活质量问卷（第4版）评估生活质量。解剖位置数据从病历中获取。使用方差分析测试比较根据肿瘤位置的生活质量差异。
总共纳入了144名参与者，其中66名（45.5%）原发性肿瘤位于口腔。患者的中位年龄为62岁，男性（75.7%）、黑人（78.5%）、单身/离婚/丧偶者（59%）和文盲（32.6%）的患病率较高；他们中的大多数是吸烟者（84.7%）和饮酒者（79.2%）。口腔癌患者的平均生活质量得分为830分，咽癌患者为858分，喉癌患者为891分。
根据本研究结果，可以得出结论，头颈癌患者的生活质量不受肿瘤位置的影响。三组中受影响最大的领域是疼痛、外观、咀嚼、吞咽和言语（<0.05）。
