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英国一家高容量中心的 980 例连续腹主动脉瘤开放手术患者结局。

Open Surgery for Abdominal Aortic Aneurysm: 980 Consecutive Patient Outcomes from a High-Volume Centre in the United Kingdom.

机构信息

Belfast Vascular Centre, Royal Victoria Hospital, Belfast Health and Social Care Trust, Belfast, UK.

Royal College of Surgeons in Ireland University of Medicine and Health Sciences, Dublin, Ireland.

出版信息

Vasc Endovascular Surg. 2023 Jul;57(5):463-470. doi: 10.1177/15385744221149585. Epub 2023 Jan 30.

Abstract

BACKGROUND

Controversy persists regarding the optimal treatment for large abdominal aortic aneurysm (AAA), highlighted by the publication of the National Institute for Health and Care Excellence (NICE) guideline (NG156) on March 2020. The pendulum of opinion swings once more from endovascular to open surgical treatment. We report our experience over the last 15 years in treating consecutive AAA by open surgery.

METHODS

A retrospective review of a prospectively collected vascular database of all patients undergoing infra-renal open abdominal aortic aneurysm repair (OR) repair from 2004 to 2019 at the largest aneurysm centre in the United Kingdom. OR for elective and emergency (ruptured and symptomatic) outcomes included early morbidity and 30-day mortality, and long-term survival.

RESULTS

1017 patients underwent OR between 2004-2019, on application of our inclusion-criteria 994 patients formed our cohort for analysis (81.2% male) with a mean age 73.6 ± 7.8 years treated by OR for AAA. In that group 672 were elective and 308 were emergency (for ruptured or symptomatic). Overall 30 day mortality was 11.3%, elective 30 day mortality was 2.5%, and emergency 30 day mortality was 29.9%. 30 day re-intervention rate was 9.5%, (elective 7.0%, emergency 15.9%). Survival at 1000 days for elective repair was 72 v 46.7% for emergency and at 2000 days was 43.4% for elective v 25% for emergency.

CONCLUSION

Our data confirm that open surgery for AAA can be performed in large volume centres quite safely. Elective and Emergency surgery does affect early 30 day mortality but does not influence long-term outcome.

摘要

背景

2020 年 3 月,英国国家卫生与保健优化研究所(NICE)发布指南(NG156),该指南对大型腹主动脉瘤(AAA)的最佳治疗方法仍存在争议。人们的观点再次从血管内治疗转向开放手术治疗。我们报告了过去 15 年来在英国最大的动脉瘤中心连续采用开放手术治疗 AAA 的经验。

方法

回顾性分析 2004 年至 2019 年期间,在英国最大的动脉瘤中心连续采用开放手术治疗的所有接受肾下腹主动脉瘤修复(OR)修复的患者的前瞻性收集的血管数据库。OR 用于治疗择期和紧急(破裂和有症状)结果,包括早期发病率和 30 天死亡率以及长期生存率。

结果

2004 年至 2019 年期间,有 1017 名患者接受了 OR,根据纳入标准,994 名患者符合我们的分析队列(81.2%为男性),平均年龄为 73.6 ± 7.8 岁,因 AAA 接受 OR 治疗。在该组中,672 例为择期,308 例为紧急(破裂或有症状)。总体 30 天死亡率为 11.3%,择期 30 天死亡率为 2.5%,紧急 30 天死亡率为 29.9%。30 天再干预率为 9.5%(择期 7.0%,紧急 15.9%)。择期修复的 1000 天生存率为 72%,紧急修复为 46.7%,2000 天生存率为 43.4%,紧急修复为 25%。

结论

我们的数据证实,在大型容量中心进行 AAA 的开放手术非常安全。择期和紧急手术确实会影响早期 30 天死亡率,但不会影响长期结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/026a/10240622/37171b299f06/10.1177_15385744221149585-fig1.jpg

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