Food Standards Agency, London, UK
Food Standards Agency, London, UK.
BMJ Open Gastroenterol. 2023 Jan;10(1). doi: 10.1136/bmjgast-2022-001009.
Mathematical models have gained traction when estimating cases of foodborne illness. Model structures vary due to differences in data availability. This begs the question as to whether differences in foodborne illness rates internationally are real or due to differences in modelling approaches.Difficulties in comparing illness rates have come into focus with COVID-19 infection rates being contrasted between countries. Furthermore, with post-EU Exit trade talks ongoing, being able to understand and compare foodborne illness rates internationally is a vital part of risk assessments related to trade in food commodities.
We compared foodborne illness estimates for the United Kingdom (UK) with those from Australia, Canada and the USA. We then undertook sensitivity analysis, by recreating the mathematical models used in each country, to understand the impact of some of the key differences in approach and to enable more like-for-like comparisons.
Published estimates of overall foodborne illness rates in the UK were lower than the other countries. However, when UK estimates were adjusted to a more like-for-like approach to the other countries, differences were smaller and often had overlapping credible intervals. When comparing rates by specific pathogens, there were fewer differences between countries. The few large differences found, such as virus rates in Canada, could at least partly be traced to methodological differences.
Foodborne illness estimation models are country specific, making international comparisons problematic. Some of the disparities in estimated rates between countries can be shown to be attributed to differences in methodology rather than real differences in risk.
数学模型在估计食源性疾病病例方面已经得到了广泛应用。由于数据可用性的差异,模型结构也有所不同。这就引出了一个问题,即国际上食源性疾病发病率的差异是真实存在的,还是由于建模方法的差异造成的。随着 COVID-19 感染率在各国之间的对比,比较发病率的困难已经成为焦点。此外,随着脱欧后贸易谈判的进行,能够理解和比较国际食源性疾病发病率是与食品商品贸易相关的风险评估的重要组成部分。
我们比较了英国(UK)、澳大利亚、加拿大和美国的食源性疾病估计值。然后,我们通过重新创建每个国家使用的数学模型进行敏感性分析,以了解方法上的一些关键差异的影响,并实现更相似的比较。
英国发表的总体食源性疾病发病率估计值低于其他国家。然而,当将英国的估计值调整为更类似于其他国家的方法时,差异较小,且通常具有重叠的可信区间。当按特定病原体比较发病率时,各国之间的差异较小。在加拿大发现的一些较大的差异,如病毒率,至少部分可以归因于方法学上的差异。
食源性疾病估计模型是针对特定国家的,这使得国际比较变得复杂。一些国家之间估计发病率的差异可以归因于方法学上的差异,而不是风险的真实差异。