非发酵革兰氏阴性杆菌对美罗培南-法硼巴坦和德拉沙星的敏感性。
susceptibility of nonfermenting Gram-negative rods to meropenem-vaborbactam and delafloxacin.
机构信息
Service de Biologie Clinique, Hôpital Foch, 92150, Suresnes, France.
Service de Bactériologie et des Contrôles Microbiologiques, CHU de Nantes, 44000, Nantes, France.
出版信息
Future Microbiol. 2023 Jan;18:117-126. doi: 10.2217/fmb-2021-0278. Epub 2023 Feb 1.
Meropenem-vaborbactam and delafloxacin activities were not assessed against spp. (), complex () and (). A total of 106 , 57 and 100 were tested with gradient diffusion test of meropenem-vaborbactam, delafloxacin and comparators. Meropenem-vaborbactam MIC were 4 μg/ml for , 1 μg/ml for , 2 μg/ml for and , and 32 μg/ml for . Delafloxacin MIC were 4 μg/ml for , 0.25 μg/ml for and , 2 μg/ml for , and 0.5 μg/m for . meropenem-vaborbactam MICs were fourfold lower than meropenem for 28.3% , 77.2% , 53.8% and 77.2% . Meropenem-vaborbactam and delafloxacin are active against and .
美罗培南-法硼巴坦和德拉沙星对 spp.（）、 复合体（）和 （）不进行评估。使用美罗培南-法硼巴坦、德拉沙星和对照品的梯度扩散试验，共测试了 106 株 、57 株 和 100 株 。美罗培南-法硼巴坦对 、 、 和 的 MIC 分别为 4μg/ml、1μg/ml、2μg/ml 和 32μg/ml。德拉沙星对 、 、 和 的 MIC 分别为 4μg/ml、0.25μg/ml、2μg/ml 和 0.5μg/ml。美罗培南-法硼巴坦对 28.3%、77.2%、53.8%和 77.2%的 MIC 比美罗培南低 4 倍。美罗培南-法硼巴坦和德拉沙星对 和 均具有活性。
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