PhD Science Writer, New York, New York, USA.
Division of Pulmonary and Critical Medicine, Department of Medicine; Department of Immunology; and Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA.
Ann N Y Acad Sci. 2023 Apr;1522(1):60-73. doi: 10.1111/nyas.14958. Epub 2023 Feb 1.
Respiratory viruses are a common cause of morbidity and mortality around the world. Viruses like influenza, RSV, and most recently SARS-CoV-2 can rapidly spread through a population, causing acute infection and, in vulnerable populations, severe or chronic disease. Developing effective treatment and prevention strategies often becomes a race against ever-evolving viruses that develop resistance, leaving therapy efficacy either short-lived or relevant for specific viral strains. On June 29 to July 2, 2022, researchers met for the Keystone symposium "Respiratory Viruses: New Frontiers." Researchers presented new insights into viral biology and virus-host interactions to understand the mechanisms of disease and identify novel treatment and prevention approaches that are effective, durable, and broad.
呼吸道病毒是全球发病率和死亡率的常见原因。流感、呼吸道合胞病毒和最近的 SARS-CoV-2 等病毒可以在人群中迅速传播,导致急性感染,在脆弱人群中,引发严重或慢性疾病。制定有效的治疗和预防策略往往是与不断进化的病毒之间的一场竞赛,这些病毒会产生耐药性,导致治疗效果要么短暂,要么只针对特定的病毒株。2022 年 6 月 29 日至 7 月 2 日,研究人员举行了基斯通研讨会“呼吸道病毒:新前沿”。研究人员提出了对病毒生物学和病毒-宿主相互作用的新见解,以了解疾病的机制,并确定有效、持久和广谱的新型治疗和预防方法。