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基于二维材料的可穿戴化学传感器在医疗保健中的应用。

Wearable chemical sensors based on 2D materials for healthcare applications.

机构信息

School of Industrial Engineering, Purdue University, West Lafayette, Indiana 47907, USA.

Flex Laboratory, Purdue University, West Lafayette, Indiana 47907, USA.

出版信息

Nanoscale. 2023 Feb 16;15(7):3079-3105. doi: 10.1039/d2nr05447g.

DOI:10.1039/d2nr05447g
PMID:36723394
Abstract

Chemical sensors worn on the body could make possible the continuous, noninvasive, and accurate monitoring of vital human signals, which is necessary for remote health monitoring and telemedicine. Attractive for creating high-performance, wearable chemical sensors are atomically thin materials with intriguing physical features, abundant chemistry, and high surface-to-volume ratios. These advantages allow for appropriate material-analyte interactions, resulting in a high level of sensitivity even at trace analyte concentrations. Previous review articles covered the material and device elements of 2D material-based wearable devices extensively. In contrast, little research has addressed the existing state, future outlook, and promise of 2D materials for wearable chemical sensors. We provide an overview of recent advances in 2D-material-based wearable chemical sensors to overcome this deficiency. The structure design, manufacturing techniques, and mechanisms of 2D material-based wearable chemical sensors will be evaluated, as well as their applicability in human health monitoring. Importantly, we present a thorough review of the current state of the art and the technological gaps that would enable the future design and nanomanufacturing of 2D materials and wearable chemical sensors. Finally, we explore the challenges and opportunities associated with designing and implementing 2D wearable chemical sensors.

摘要

佩戴在身上的化学传感器可以实现对重要人体信号的连续、非侵入式和精确监测,这对于远程健康监测和远程医疗是必要的。原子层厚度的材料具有诱人的物理特性、丰富的化学性质和高的表面积与体积比,非常适合制造高性能的可穿戴化学传感器。这些优势允许适当的材料-分析物相互作用,即使在痕量分析物浓度下也能达到高灵敏度。以前的综述文章广泛涵盖了基于二维材料的可穿戴设备的材料和器件元件。相比之下,很少有研究涉及二维材料在可穿戴化学传感器中的现有状态、未来展望和潜力。我们提供了基于二维材料的可穿戴化学传感器的最新进展概述,以克服这一不足。将评估基于二维材料的可穿戴化学传感器的结构设计、制造技术和机制,以及它们在人体健康监测中的适用性。重要的是,我们对当前的技术水平进行了全面的回顾,并探讨了未来设计和纳米制造二维材料和可穿戴化学传感器所需的技术差距。最后,我们探讨了设计和实现二维可穿戴化学传感器所面临的挑战和机遇。

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