Department of Physiology and Biophysics, University of Colorado Anschutz Medical Campus , Aurora, CO, USA.
J Gen Physiol. 2023 Mar 6;155(3). doi: 10.1085/jgp.202213307. Epub 2023 Feb 1.
Molecular dynamics simulations reveal a putative interaction surface for PUFAs on TM1 of ASICs that is not tightly conserved between isoforms.
分子动力学模拟揭示了 ASICs 跨膜域 1 上 PUFAs 的一个假定相互作用表面,该表面在不同亚型之间没有严格保守。