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2020-2022 年丹麦成年人的视力和中心视力丧失原因。来自 FORSYN 研究的结果。

Visual acuity and causes of central visual loss in the adult Danish population 2020-2022. Results from the FORSYN study.

机构信息

Department of Ophthalmology, Aarhus University Hospital, Aarhus N, Denmark.

Department of Public Health, University of Aarhus, Aarhus C, Denmark.

出版信息

Acta Ophthalmol. 2023 Aug;101(5):504-513. doi: 10.1111/aos.15641. Epub 2023 Feb 1.

DOI:10.1111/aos.15641
PMID:36726309
Abstract

PURPOSE

Knowledge of visual health in the population is necessary for designing and implementing measures to handle visual handicap. The purpose of the FORSYN (Forekomst af synshandicap og synshjaelpemidler i Danmark) project was to study visual health in the Danish population 2020-2022 after implementation of the recent advances in the management of choroidal and retinal vascular disease. The present study reports visual acuity and causes of central visual loss from this study.

METHODS

A population-representative sample of 10 350 citizens living within 40 kilometres from Aarhus University Hospital were invited to answer a questionnaire about quality of life related to vision, measurement of visual acuity and a non-mydriatic examination of the eyes. The data were corrected for selection bias on the basis of demographic and socioeconomic factors so that the results could be projected to represent the adult Danish population.

RESULTS

Population-adjusted visual acuity in ETDRS letters (mean ± SD) differed significantly (p < 0.0001) among the worse eye (84.1 ± 0.25), the better eye (88.4 ± 0.11) and binocularly (89.2 ± 0.15). Social blindness affected 0.22% (95% CI: 0.14%-0.33%) of the population and was in none of the studied persons due to exudative age-related macular degeneration (AMD) or diabetic retinopathy. The most frequent causes of visual loss were atrophic AMD, neuro-ophthalmic disorders and other chorioretinal diseases.

CONCLUSIONS

Recent advances in the therapy of chorioretinal vascular diseases have been paralleled with a reduction in central vision loss secondary to exudative AMD and diabetic retinopathy in Denmark. The demographic development can be expected to increase the demand for treatments of vision-threatening diseases that mainly affect older persons.

摘要

目的

了解人群的视觉健康对于设计和实施处理视觉障碍的措施至关重要。FORSYN(丹麦脉络膜和视网膜血管疾病管理新进展后 2020-2022 年的视觉健康研究)项目的目的是研究丹麦人群的视觉健康。本研究报告了来自该研究的中心视力丧失的视力和原因。

方法

邀请居住在奥胡斯大学医院 40 公里范围内的 10350 名具有代表性的公民回答一份与视力相关的生活质量问卷,测量视力,并对眼睛进行非散瞳检查。根据人口统计学和社会经济因素对数据进行选择偏差校正,以便结果可以代表丹麦成年人口。

结果

校正后的 ETDRS 字母视力(平均值±标准差)在较差眼(84.1±0.25)、较好眼(88.4±0.11)和双眼(89.2±0.15)之间存在显著差异(p<0.0001)。社会失明影响 0.22%(95%置信区间:0.14%-0.33%)的人群,且研究人群中没有因渗出性年龄相关性黄斑变性(AMD)或糖尿病性视网膜病变而失明的人。视力丧失的最常见原因是萎缩性 AMD、神经眼科疾病和其他脉络膜视网膜疾病。

结论

丹麦脉络膜和视网膜血管疾病治疗的新进展与渗出性 AMD 和糖尿病性视网膜病变导致的中心视力丧失减少相平行。人口统计学的发展预计会增加对主要影响老年人的威胁视力疾病的治疗需求。

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