Kartsonaki Christiana, Cox D R
MRC Population Health Research Unit, Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK.
Nuffield College, Oxford OX1 1NF, UK.
Econom Stat. 2023 Jan;25:87-92. doi: 10.1016/j.ecosta.2020.10.003.
The simplest form of retrospective study allows the reconstruction of the dependence between a binary outcome, representing the contrast between cases and controls, and one or more explanatory variables. A different objective for such situations is considered, in which there are distinct explanatory variables, say determining . Reconstruction of the originating distribution of from the case-control data is considered for both continuous and binary variables. Emphasis is on the linear regression coefficient of on . That coefficient, but not the relevant intercept, shows considerable stability, as shown by theory and simulations. An approximation to the value of the coefficient not conditioning on is given.
回顾性研究的最简单形式允许重建二元结局（代表病例与对照之间的对比）与一个或多个解释变量之间的依存关系。对于此类情况，考虑了一个不同的目标，即存在不同的解释变量，比如确定……。对于连续变量和二元变量，均考虑从病例对照数据重建……的原始分布。重点在于……对……的线性回归系数。如理论和模拟所示，该系数而非相关截距显示出相当的稳定性。给出了不依赖于……的系数值的一个近似值。
