From the Department of Plastic, Reconstructive, and Aesthetic Surgery, Kecioren Research and Training Hospital.
Departments of Plastic, Reconstructive, and Aesthetic Surgery.
Plast Reconstr Surg. 2023 Jun 1;151(6):1233-1241. doi: 10.1097/PRS.0000000000010134. Epub 2023 Jan 2.
Microneedling promotes percutaneous collagen induction; cupping therapy creates negative pressure and leads to increased blood flow in the applied area. The addition of cupping therapy to microneedling is thought to contribute positively to microneedling's effects. This study was carried out to investigate the histologic effects of adding cupping therapy to microneedling.
Thirty Wistar rats were divided into five groups, with six rats in each group. One control group and four experimental groups were formed, which are defined as follows: the control group; the single-session microneedling applied to the dorsal trunk group; the 15-minute cupping therapy added to the single-session microneedling group; the microneedling applied over a total of three sessions at 3-week intervals group; and the microneedling with cupping therapy applied over a total of three sessions at 3-week intervals group. Each animal was euthanized at the end of the fourth week following the last treatment, and skin samples were evaluated histologically with hematoxylin and eosin stain and type I and III collagen antibody immunostaining.
The addition of cupping therapy to microneedling increased the thickness of the epidermis and dermis. A significant increase in type I collagen immunostaining and the type-I-to-type III collagen ratio was seen only in the single-session microneedling applied to the dorsal trunk group. Cupping therapy did not generate a significant difference in type I collagen immunostaining. No treatment was found to produce a significant increase in type III collagen immunostaining.
Cupping therapy can be added to microneedling therapy and used to increase certain desired effects on skin.
Microneedling is an easy and effective method to improve skin quality in clinical practice.
微针刺促进经皮胶原诱导；拔罐疗法产生负压，导致应用区域血流量增加。在微针刺中添加拔罐疗法被认为对微针刺的效果有积极的贡献。本研究旨在探讨在微针刺中添加拔罐疗法的组织学效果。
将 30 只 Wistar 大鼠分为五组，每组 6 只。形成一个对照组和四个实验组，具体如下：对照组；单次背部微针刺组；单次微针刺加 15 分钟拔罐组；3 周间隔共进行 3 次微针刺组；3 周间隔共进行 3 次微针刺加拔罐组。每组动物在最后一次治疗后第 4 周结束时处死，用苏木精和伊红染色及 I 型和 III 型胶原抗体免疫染色对皮肤标本进行组织学评估。
在微针刺中添加拔罐疗法增加了表皮和真皮的厚度。仅在单次背部微针刺组中观察到 I 型胶原免疫染色和 I 型/III 型胶原比值显著增加。拔罐疗法对 I 型胶原免疫染色没有产生显著差异。没有一种治疗方法能显著增加 III 型胶原免疫染色。
拔罐疗法可添加到微针刺疗法中，用于增加皮肤的某些预期效果。
微针刺是一种在临床实践中改善皮肤质量的简单有效方法。
