Federal University of Rio Grande do Norte, Natal, Brazil.
Rio Grande do Norte University Centre (UNIRN), Natal, Brazil.
Photodermatol Photoimmunol Photomed. 2021 Nov;37(6):521-529. doi: 10.1111/phpp.12704. Epub 2021 Jun 16.
Microneedling promotes skin microlesions that lead to an inflammatory process, increasing cell proliferation, cell metabolism, and synthesis of collagen and elastin, therefore restoring skin integrity.
This study aims to investigate the differences between the physical and the physical-chemical sunscreen application after microneedling, assessed through histological analysis.
This was a two-phase study. The first phase investigated the physical and physical-chemical sunscreen penetration mixed with India ink through histological analysis. The sunscreens were applied after the microleakage in vivo on the skin of a volunteer who underwent abdominoplasty 24 hours after the procedure. Histological analyses were carried out using optical and electron microscopy. The second phase analysed the skin reactions with the use of physical sunscreen after different microneedling treatments. The sample consisted of 30 volunteers distributed into three groups: G1 received the "Roller" microneedling, G2 received pen micropuncture treatment, and G3 received the fractional radiofrequency treatment.
The histological analyses of the first phase indicated that the physical-chemical protection sunscreen penetrated more deeply, and pigment was found among the collagen fibres and the dermal fibroblast cytoplasm in comparison to the physical protection sunscreen, which had the pigment confined exclusively in the superficial epidermis layer. The second phase results demonstrated that the use of the physical protection sunscreen after the different microneedling techniques showed no adverse reactions such as itching, pain or soreness, and the hyperaemia.
The proposed intervention showed that the use of physical protection sunscreen after different microneedling procedures is safe.
微针刺激会导致皮肤微损伤，从而引发炎症反应，增加细胞增殖、细胞代谢以及胶原蛋白和弹性蛋白的合成，从而恢复皮肤完整性。
本研究旨在通过组织学分析，研究微针治疗后物理和物理化学防晒霜应用的差异。
这是一项两阶段研究。第一阶段通过组织学分析研究了与印度墨混合的物理和物理化学防晒霜的渗透情况。在志愿者腹部整形术后 24 小时进行体内微渗漏后，将防晒霜应用于皮肤。使用光学显微镜和电子显微镜进行组织学分析。第二阶段分析了不同微针治疗后使用物理防晒霜引起的皮肤反应。样本由 30 名志愿者组成，分为三组：G1 组接受“滚轮”微针治疗，G2 组接受笔状微穿刺治疗，G3 组接受分数射频治疗。
第一阶段的组织学分析表明，物理化学防晒剂渗透得更深，与物理防晒剂相比，颜料被发现存在于胶原纤维和真皮成纤维细胞的细胞质中，而物理防晒剂的颜料仅局限于表皮的浅层。第二阶段的结果表明，在不同的微针技术后使用物理防晒剂没有引起不良反应，如瘙痒、疼痛或压痛和红斑。
所提出的干预措施表明，在不同的微针治疗后使用物理防晒剂是安全的。
